Vesicle release from photoreceptor ribbon synapses is regulated by L-type Ca(2+) channels, which are in turn regulated by Cl(-) moving through calcium-activated chloride [Cl(Ca)] channels. We assessed the proximity of Ca(2+) channels to release sites and Cl(Ca) channels in synaptic terminals of salamander photoreceptors by comparing fast (BAPTA) and slow (EGTA) intracellular Ca(2+) buffers. BAP...

Transmembrane protein (TMEM)16A channels are recently discovered membrane proteins that display electrophysiological properties similar to classic Ca(2+)-activated Cl(-) (Cl(Ca)) channels in native cells. The molecular identity of proteins that generate Cl(Ca) currents in smooth muscle cells (SMCs) of resistance-size arteries is unclear. Similarly, whether cerebral artery SMCs generate Cl(Ca) c...

q-mode hierarchical cluster (hca) and principal component analysis (pca) were simultaneously applied to groundwater hydrochemical data from the three times in 2004: june, september, and december, along the ain azel aquifer, algeria, to extract principal factors corresponding to the different sources of variation in the hydrochemistry, with the objective of defining the main controls on the h...

Semi-Solid Casting (SSM) is a new process that could produce globular structures with mechanical properties. The cooling slope method (CLM) is a one of this process that was employed to produce the A360 feedstock. In this method, The dendritic primary phase in the conventionally cast A356 alloy has transformed into a non-dendritic one. In this paper, The molten alloy with the temperature (PT) o...

todays, the world development is facing serious water quality issues. since protect of water quality and ecosystem healthy is an important aspect of ecohydrology. the present research aimed to analyze the temporal trends of water quality parameters of mashin zard river station in order to planning long term management approaches. in this research, trend of some significant factors of water qual...

Intracellular Ca(2+) is actively sequestered into the sarcoplasmic reticulum (SR), whereas the release of Ca(2+) from the SR can be triggered by activation of the inositol 1,4,5-trisphosphate and ryanodine receptors. Uptake and release of Ca(2+) across the SR membrane are electrogenic processes; accumulation of positive or negative charge across the SR membrane could electrostatically hinder th...

Chlorine (Cl) is a constituent of certain types of nuclear wastes and its presence can affect the physical and chemical properties of silicate melts and glasses developed for the immobilization of such wastes. Cl K-edge X-ray absorption spectra (XAS) were collected and analyzed to characterize the unknown Cl environments in borosilicate waste glass formulations, ranging in Cl-content from 0.23 ...