نتایج جستجو برای: cell maturation antigen
تعداد نتایج: 1830672 فیلتر نتایج به سال:
the wharton’s jelly of the umbilical cord is believed to be a source of mesenchymal stem cells (mscs) which can be therapeutically applied in degenerative diseases. in this study, we investigated the immunomodulatory effect of umbilical cord derived- mesenchymal stem cells (uc-mscs) and bone marrow-derived-mesenchymal stem cells (bm-mscs) on differentiation, maturation, and endocytosis of m...
back ground: candida albicans is a member of the normal human microflora. c. albicans cell wall is composed of several protein and carbohydrate components which have been shown to play a crucial role in c. albicans interaction with the host immune system. major components of c. albican cell wall are carbohydrates such as mannans, β glucans and chitins, and proteins that partially modulate the h...
objective: menstrual blood stromal stem cells (mbscs) share some phenotypic and functional similarities with mesenchymal stem cells (mscs). mscs are shown to inhibit either the function or generation of different immune cells, including dendritic cells (dcs). however, data regarding mbscs’ potential effects on immune system cells are elusive. here, we examine whether mbscs affect the generation...
Naturally evolving antibodies attain elevated affinity in germinal centers (GCs).[1] In these dynamic open micro-structures, competition between B cell clones and their somatic mutants drives an increase average across individual populations of up to a few thousand cells. Such evolutionary learning the antigenic target (known as maturation), however, eventually saturates. Most notably, saturati...
Abstract TARM1 is a member of the leukocyte immunoglobulin-like receptor family and stimulates macrophages neutrophils in vitro by associating with FcR?. However, function this molecule regulation immune system unclear. Here, we show that Tarm1 expression elevated joints rheumatoid arthritis mouse models, development collagen-induced (CIA) suppressed –/– mice. T cell priming against type 2 coll...
Dendritic cells (DCs) are the most potent antigen-presenting cells. Upon maturation, DCs express costimulatory molecules and migrate to lymph nodes present antigens T The actin cytoskeleton plays key roles in multiple aspects of DC functions. However, little is known about mechanisms identities actin-binding proteins that control maturation maturation-associated functional changes. Tropomodulin...
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Abstract Background and purpose: Different laboratories have considered different maturation factors for producing human dendritic cells (DC) from peripheral blood monocytes. In this study, we comprehensively investigated the effect of adding poly (I:C) to standard maturation stimulus, i.e. MCM and TNF-α on the induction of T cell response. Materials and methods: Peripheral blood monocytes ...
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