objective(s): production of a recombinant and immunogenic antigen using dengue virus type-3 envelope protein is a key point in dengue vaccine development and diagnostic researches. the goals of this study were providing a recombinant protein from dengue virus type-3 envelope protein and evaluation of its immunogenicity in mice. materials and methods: multiple amino acid sequences of different i...

Dengue fever is a mosquito-borne infection which is endemic in Southeast Asia. Although it has not been distributed in Iran, locating near other countries where the Dengue has been revealed is a threat for Iran because different connection between countries may increase the rate of infection.

in southeast asia, aedes aegypti (l.) has been incriminated as principal vector of dengue viruses and ae. albopictus as the secondary vector of dengue fever. therefore, the aim of this study was to investigate the effectiveness of three for-mula tions of pyrethrin derived from tanacetum cinerariaefolium against the dengue/dengue haemorrhagic fever vectors aedes aegypti and ae. albopictus in the...

background: the aim of this study was to assess community knowledge and behavioral impact of the social mobili­zation and communication strategy applied in a dengue high-risk area in sri lanka. methods: a group of adults visiting selected primary care facilities in colombo district were interviewed to collect socio-demographicdata, attributes of knowledge regarding dengue and the responsive beh...

introductio dengue fever is the world’s most important hemorrhagic fever, especially in america, pacific islands, and asia. in countries like ours where viral hepatitis, malaria, enteric fever are common; it represents a challenge to identify the etiology of acute fever complicated by hepatitis. case presentation we report a case of acute hepatitis in a 7-year-old male with dengue hemorrhagic f...

Background: Dengue fever is a mosquito-borne disease which is not known to be endemic in Iran. Case Report: In October 2015, a 32-year-old Iranian woman was admitted with acute unexplained high-grade fever, headache, pain, rash, diarrhea, leukopenia and elevated liver enzymes after returning from India. Serological and molecular analysis for Dengue virus (DENV) infection revealed positive ...

Background: Fluid resuscitation is the mainstay of treatment to counteract massive plasma leakage in dengue shock syndrome. We aimed to determine the differences in clinical outcomes and hemodynamic parameters of children with dengue shock syndrome post restrictive and liberal fluid resuscitation.  Materials and Methods: A retrospective observational study of pediatric patients who were betwee...

background: dengue is amongst the most serious mosquito-borne infectious disease with hot spots in tropical and subtropical parts of the world. unfortunately, no licensed vaccine for the disease is currently available in medicine markets. the only option available is the management of dengue vector mosquito, aedes aegypti (diptera: culicidae). method: predatory potential of five odonate nymphs ...

Background and Objective: Dengue virus infection remains a health problem. Dengue Virus Non-Structural protein 1 (NS1) increases the release of proinflammatory cytokines that induce intestinal zonulin expression. As a result, the ZO-1 protein translocates to the cytoplasm, which increases enterocyte permeability. This study aimed to investigate the effects of dengue NS1 on intestinal zonulin an...