نتایج جستجو برای: hepatic toxicity

تعداد نتایج: 208334  

2012
Takeshi Sugimoto Yumiko Nobuhara Seiji Kawano Akio Morinobu

Trimethoprim-Sulfamethoxazole (TMP-SMZ) is associated with severe hepatic toxicity or liver failure. We present a case of severe hepatic toxicity for whom TMP-SMZ was prescribed as part of treatment for mixed connective tissue disease (MCTD). TMP-SMZ was used to prevent complications from steroid therapy, but fever and hepatic toxicity developed with repeated TMP-SMZ medication. While the drug ...

Journal: :Blood 2010
Daisuke Ennishi Yoshinobu Maeda Nozomi Niitsu Minoru Kojima Koji Izutsu Jun Takizawa Shigeru Kusumoto Masataka Okamoto Masahiro Yokoyama Yasushi Takamatsu Kazutaka Sunami Akira Miyata Kayoko Murayama Akira Sakai Morio Matsumoto Katsuji Shinagawa Akinobu Takaki Keitaro Matsuo Tomohiro Kinoshita Mitsune Tanimoto

The influence of hepatitis C virus (HCV) infection on prognosis and hepatic toxicity in patients with diffuse large B-cell lymphoma in the rituximab era is unclear. Thus, we analyzed 553 patients, 131 of whom were HCV-positive and 422 of whom were HCV-negative, with DLBCL treated with rituximab, cyclophosphamide, doxorubicin, vincristine, and prednisone (RCHOP)-like chemotherapy. Survival outco...

Acetaminophen (APAP) toxicity threatens human health due to increased mortality associated with its overdose. Doxycycline (DC) because of its properties such as antioxidant and anti-inflammatory can be a good therapeutic strategy to treat the acute toxicity induced by APAP. Male mice were divided to six groups in two periods of 3 and 24-h as normal saline, APAP 400 mg/kg, DC 100 mg/kg and group...

Acetaminophen (APAP) toxicity threatens human health due to increased mortality associated with its overdose. Doxycycline (DC) because of its properties such as antioxidant and anti-inflammatory can be a good therapeutic strategy to treat the acute toxicity induced by APAP. Male mice were divided to six groups in two periods of 3 and 24-h as normal saline, APAP 400 mg/kg, DC 100 mg/kg and group...

EUGENE J. KUCHARZ, THERESA KOTT,

Rats were treated with acetylsalicylic acid (150 mgikg b.w.per os daily) or naproxen (125 mg/kg b.w. per os daily) for six weeks. Half of the rats received silymarin (17.5 mgikg b.w. per os daily) in the last three weeks of the experiment. It was found tliat administration of acetylsalicylic acid led to signs of hepatic damage (an increase in serum bilirubin level, alanine aminotransferase ...

Journal: :anesthesiology and pain medicine 0
hassan soleimanpour cardiovascular research center, tabriz university of medical sciences, tabriz, iran saeid safari department of anesthesiology, iran university of medical sciences, tehran, iran farzad rahmani road traffic injury research center, tabriz university of medical sciences, tabriz, iran hoorolnesa ameli students’ research committee, tabriz university of medical sciences, tabriz, iran seyed moayed alavian hepatitis b molecular laboratory, department of virology, school of public health, tehran university of medical sciences, tehran, iran; hepatitis b molecular laboratory, department of virology, school of public health, tehran university of medical sciences, tehran, iran. tel: +98-2188945186, fax: +98-2188945188

conclusions despite the adverse effects of inhalational halogenated anesthetics (especially halothane) on hepatic patients when necessary. the effects on all systems must be considered and the necessary preparations must be provided. these drugs are still used, if necessary, due to the presence of positive effects and advantages mentioned in other studies as well as the adverse effects of other...

Journal: :medical journal of islamic republic of iran 0
eugene j. kucharz from the fourth department of internal medicine, silesian university, scool of medicine, ul. edukacji 102, pl 43-100 tychy, poland. theresa kott

rats were treated with acetylsalicylic acid (150 mgikg b.w.per os daily) or naproxen (125 mg/kg b.w. per os daily) for six weeks. half of the rats received silymarin (17.5 mgikg b.w. per os daily) in the last three weeks of the experiment. it was found tliat administration of acetylsalicylic acid led to signs of hepatic damage (an increase in serum bilirubin level, alanine aminotransferase and ...

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