Abbreviations: ALT: Alanine Transaminase; AST: Aspartate Transaminase; BMI: Body Mass Index; CMV: Cytomegalovirus; Cnis: Calcineurin Inhibitors; Csa: Cyclosporine; FK Or FK-506: Tacrolimus; GRWR: Graft Recipient Weight Ratio; HAI: Histological Activity Index; HCC: Hepatocellular Carcinoma; HCV: Hepatitis C Virus; HCV RNA: Hepatitis C Virus Ribonuclic Acid; HPB: Hepatopancreatobiliary;LDLT: Livi...

background: hepatic steatosis is commonly observed in patients with chronic hepatitis c (chc). many studies indicate a relationship between steatosis and fibrosis progression. the aim of this study was to analyze the prevalence of hepatic steatosis and related factors in iranian chc patients.   methods: one hundred and fifteen consecutive patients with chc were enrolled which were treatment-naï...

Background: The prognosis and management of patients with chronic hepatitis B depend on the amount and progression of the liver fibrosis. Liver biopsy is currently the gold standard for staging of fibrosis and histological activity, but it is poor tolerated. Noninvasive methods are now used increasingly to reduce the need for liver biopsy. Our aim is to validate simpler model, consisting of rou...

AIMS To study the synergistic effect of occupational chemical exposure and hepatitis virus infection on serum aminotransferase activity. METHODS A total of 568 male workers who were employed in five polyvinyl chloride (PVC) or four vinyl chloride monomer (VCM) manufacturing factories were studied. Information relating to current job title, alcohol consumption, and cigarette smoking was obtain...

BACKGROUND/AIMS To investigate the relationship between gamma-glutamyl transpeptidase (GGT) levels and histopathological status determined by biopsy in patients with chronic hepatitis B and C. MATERIALS AND METHODS Patients with chronic hepatitis B and C who were referred to the Uludağ University Faculty of Medicine Gastroenterology outpatient clinic between January 2005-January 2011 and unde...

BACKGROUND The mean platelet volume (MPV) is the most commonly used measure of platelet size and is a potential marker of platelet reactivity. In this study, we aimed to explore the relationship between hepatic histopathology in viral hepatitis and MPV levels, which are associated with platelet count and activity. MATERIALS AND METHODS We performed a retrospective case-control study of baseli...

The cytotoxic effect of peripheral lymphocytes on chicken red blood cells (ChRBC) coated with purified hepatitis B surface antigen (HBsAg) has been studied as an in vitro parameter of cell-mediated immunity in acute and chronic infection with hepatitis B virus. Using this technique, the mean cytotoxic index of lymphocytes from patients with acute hepatitis B (29.13 +/- 20.88) was significantly ...

Background: Hepatitis activity index (HAI) and fibrosing stage are two important findings during the evaluation of liver samples in patients with chronic hepatitis B. The aim of this study was to determine the HAI and fibrosing stage in patients with anti-HBe positive chronic hepatitis B. Methods: Liver biopsy slides of 72 patients were evaluated at the Department of Pathology in two teaching ...

Background/Aim: Drug-induced liver injury is one of the major causes acute failure. Under current circumstances pandemic COVID-19, use paracetamol which has a proven hepatotoxic effect increased. This prompts search for novel agents with hepatoprotective properties. The purpose this article was to evaluate activity cryoextract placenta (CEP) on model paracetamol-induced hepatitis. Methods: stud...