Eicosapentaenoic acid (EPA)-producing Shewanella marinintestina IK-1 (IK-1) and its EPA-deficient mutant IK-1Delta8 (IK-1Delta8) were grown on microtitre plates at 20 degrees C in a nutrient medium that contained various types of growth inhibitors. The minimal inhibitory concentrations of hydrogen peroxide and tert-butyl hydroxyl peroxide were 100 microM and 1 mM, respectively, for IK-1 and 10 ...

Let t and k be a positive integers, and let Ik = {i ∈ Z : −k ≤ i ≤ k}. Let st(Ik) be the smallest positive integer ` such that every zero-sum sequence S over Ik of length |S| ≥ ` contains a zero-sum subsequence of length t. If no such ` exists, then let st(Ik) =∞. In this paper, we prove that st(Ik) is finite if and only if every integer in [1, D(Ik)] divides t, where D(Ik) = max{2, 2k − 1} is ...

1.1. Statement of the main result. The isoperimetric problem of euclidean type for a space X and given classes Ik−1, Ik, and Ik+1 of surfaces of dimension k − 1, k, and k + 1 in X , together with boundary operators Ik+1 ∂ −→ Ik ∂ −→ Ik−1 and a volume function M on each class, asks the following: Does there exist for every surface T ∈ Ik without boundary, ∂T = 0, a surface S ∈ Ik+1 with ∂S = T a...

4',4'-dimethylspiro (5 alpha-cholestane-3,2'-oxazolidin)-3'-yloxy (IK-1) and 7 alpha,12 alpha-dihydroxy-4',-4'-dimethylspiro (5 beta-cholan-24-oic-3,2'-oxazolidin)-3'-yloxy acid (IK-2), two stable steroidic nitroxyl radicals, were newly synthesized and tested as possible inhibitors of lipid peroxidation, induced by Fenton's reagent in both rat liver microsomes and egg phosphatidylcholine liposo...

Ikaros (IK) malfunction has been implicated in the pathogenesis of acute lymphoblastic leukemia (ALL), the most common form of childhood cancer. Therefore, a stringent regulation of IK activity is very important. Here we provide unique genetic and biochemical evidence that the Ku protein components Ku70 and Ku80 act as positive regulators of IK function via formation of IK-Ku70 and IK-Ku80 hete...

In der ersten Märzwoche ist jedes Jahr alles ganz anders in der Familienbildungsstätte im Heinrich-Lübke-Haus in Günne am Möhnesee. Wo letzte Woche noch Kinder spielten, bewegen sich nun Wissenschaftlern aus aller Welt. Der gesamte Komplex ist von Informatikern, über Biologen, Psychologen und Kognitionswissenschaftler bis zu Philosophen übernommen worden. Alle interessieren sich für Forschung a...