diosmin, a vascular-protecting agent, is practically insoluble in water, and its oral absorption is limited by its extremely low dissolution rate. in this study, β-cyclodextrin (βcd) and 2-hydroxypropyl-β-cyclodextrin (hpβcd) were obtained to improve the solubility and dissolution rate of diosmin. phase solubility studies of diosmin with βcd and hpβcd in distilled water were conducted to charac...

it is well known that a microperiodic function mapping a topological group into reals, which is continuous at some point is constant. we introduce the notion of a microperiodic multifunction, defined on a topological group with values in a metric space, and study regularity conditions implying an analogous result. we deal with vietoris and hausdorff continuity concepts.stability of microperiodi...

one of the methods to enhance bio-accessibility of drugs like acridone and its oxime is toform inclusion complexes with β-cyclodextrin. the formation of such complexes has beenconfirmed by changes in spectral characteristics and melting point data. the aqueous phasesolubility studies reveal 1:1 stoichiometry between the compound and, β-cyclodextrin. the studyof thermodynamic parameters like δg,...

inclusion body hepatitis (ibh) has been reported in many countries in the world. the ibh or similar cases characterized by hepatitis and presence of intra-nuclear inclusion bodies in hepatocytes have not been reported in broiler chickens in iran. this is the first report on outbreak of adenovirus-like inclusion body hepatitis in iran. on october 2012, an onset of high acute mortality in a flock...

domperidone is a widely used antiemetic, poorly water soluble drug, erratically absorbed in stomach and possess several dissolution-related problems thus it has poor bioavailability. solubility of a drug plays a very important role in dissolution and hence absorption of drug which ultimately affects its bioavailability. hence, by considering the facts related to drug, attempts have been made to...

the komshecheh barite-fluorite deposit is the product of epigenetic hydrothermal mineralizationin dolomitized limestone of middle triassic age. the deposit is structurally and lithologically controlled andoccurs predominantly as bedded stratabound replacement sheets, although the veins and solution-collapsebreccias constitute important modes of occurrence. brecciation, dolomitization, silicific...

abstractepidermal inclusion cysts are uncommon in the breast, but the consequences can besevere when these cysts occur in the breast parenchyma. here, we report two suchcases. the patient in case 1 was an 37-year-old woman with a 3-cm palpable mass inthe right breast. mammography revealed a round and smoothly outlined mass, whichindicated a benign tumor, and sonography showed an irregularly sha...

In this manuscript, we introduce  a new class of fuzzy problems, namely ``fuzzy inclusion linear systems" and   propose a fuzzy solution set for it. Then, we present a theoretical discussion about the relationship between  the fuzzy solution set of a  fuzzy inclusion linear system and the algebraic solution of a fuzzy linear system. New necessary and sufficient conditions are derived for obtain...