introduction: postoperative pain is an acute pain related to size and site of operation, patient's psychologic and physiological condition, degree of manipulation and damage of tissues. pain is an unpleasant sensory and emotional experience associated with actual or potential tissue damage. administration of opioids is one of the common techniques for postoperative pain management, but com...

conclusions intraperitoneal migration of a subfascially placed baclofen pump is a rare, yet serious complication, which has been reported only once in the literature. we advise neurosurgeons to have a low level of threshold in confirming the location of a baclofen pump with imaging and surgical exploration if necessary in order to avoid detrimental outcomes such as bowel perforation. case prese...

in critically ill infants and children, intravascular (iv) access is sometimes very difficult. in such cases intraosseous (io) infusion should be used as the method of choice. however, in practice, different problems are experienced with this procedure. to overcome the practical problems and to confirm the efficacy of io infusion in reversing hypovolemic shock, an animal model was used by emplo...

background: acute opioid overdose is a common cause of admission in emergency department. in spite of the fact that naloxone is the main therapy for decades, there are controversies about the proper way of its use. this study aimed to compare two most recommended administration modes for naloxone. methods: in this single-blind clinical trial, 80 patients with methadone overdose syndrome were ra...

Since there is no detailed hospital based incident reporting system, this study was designed to evaluate the medication errors associated with infusion pumps in intensive care unit (ICU). The investigation was conducted in a Teaching hospital in the form of a prospective, observational study. A sample size of 43 doses administered to ICU patients was chosen to enable reliable estimate of error ...

there is no randomized study carried out in order to compare their pharmacokinetic parameters although midazolam, as a sedative, has been widely administered via continuous infusion as well as intermittent bolus doses in mechanically ventilated critically ill patients. we prospectively investigated the effect of these two principal methods on pharmacokinetic parameters in 23 of mentioned patien...

conclusions this study indicated that the delivery rate accuracy of elastomeric infusion pumps is preserved after repeated usage. these laboratory findings suggested that elastomeric pumps could be safely refilled in the successive days to provide postoperative analgesia. results the mean flow rate in the three series of measurements showed a gradual increase; however, the difference was not st...

Background: Uterine bleeding is an important side effect of cesarean section which is due to non contractile uterine. The aim of this study was to compare the effect of 10% dextrose (IV infusion) and 40 IU/L oxytocin (IV infusion) on uterine contraction. Materials and Methods: This research was a double-blinded randomized clinical trial (RCT) study. 120 women were equally included in the tw...