نتایج جستجو برای: mitogenic index

تعداد نتایج: 402111  

2005
Yun-Chi YEH

The mitogenic effect of a new growth factor that we recently isolated from the acellular ascitic fluid of the Ehrlich ascites carcinoma grown in vivo was examined. We have called this fac tor EACF (Ehrlich ascites c a r c i n o m a f a c t o r ) . EACF caused in i t ia t ion of DNA s y n t h e s i s in the l iver 9 submandibular gland, exo rb i t a l lacrimal gland and epithelium of the tongue ...

Journal: :Journal of virology 1987
P Poumbourios E M Anders A A Scalzo D O White A W Hampson D C Jackson

The mitogenic activity of influenza virus is a function of the hemagglutinin (HA) molecule. Purified HA is mitogenic for murine B lymphocytes but not T lymphocytes. Furthermore, like the intact virus, HA of the H2 (but not H3) subtype is mitogenic only for B cells expressing the class II major histocompatibility complex glycoprotein I-E. Since virus bearing uncleaved HA is as mitogenic as virus...

Journal: :HERALD of North-Western State Medical University named after I.I. Mechnikov 2015

ابراهیمی, فیروز , جوادی, غلامرضا, مداح, بزرگمهر , پورانوری, سارا ,

Background and purpose: Human epidermal growth factor (hEGF) is a polypeptide of 53 amino acids with various medical application such as wound healing. The purpose of this study was cloning, expression, and purification of recombinant human EGF (rhEGF) and assessment of its mitogenic effect on NIH 3T3 cells. Materials and methods: Subcloninig of hEGF was performed in to pET24a (+). Protein e...

2015
Harinda Rajapaksha Briony E. Forbes

The insulin receptor (IR) is a tyrosine kinase receptor that can mediate both metabolic and mitogenic biological actions. The IR isoform-A (IR-A) arises from alternative splicing of exon 11 and has different ligand binding and signaling properties compared to the IR isoform-B. The IR-A not only binds insulin but also insulin-like growth factor-II (IGF-II) with high affinity. IGF-II acting throu...

Journal: :Infection and immunity 1981
R Girard R Chaby G Bordenave

Lipopolysaccharide extracted from Bordetella pertussis was mitogenic for spleen cells of endotoxin-resistant C3H/HeJ mice. Although endotoxic lipid A was inactive, mitogenic activity of lipopolysaccharide was exhibited by purified preparations of polysaccharides I and II, which constitute the carbohydrate moiety of the macromolecule. These low-molecular-weight (2,800 and 3,600) polysaccharides,...

Journal: :Biological & pharmaceutical bulletin 1998
K X Liu Y Kato T Kaku Y Sugiyama

The effect of human placental extract (HPE) on liver regeneration in rats was investigated. After intravenous administration of HPE to a-naphthylisothiocyanate (ANIT)-intoxicated rats, the labeling index in hepatocytes was significantly increased to a level 16.5 times higher than that of the control. A 1/500 dilution of HPE directly stimulated DNA synthesis of the hepatocytes in primary culture...

Journal: :Journal of Biological Chemistry 1991

Journal: :The Journal of Cell Biology 1985
R M Senior J S Huang G L Griffin T F Deuel

Because platelet-derived growth factor (PDGF) may be released at sites where neutrophil proteinases may also be released, we examined the effects of neutrophil elastase and cathepsin G upon the chemotactic and mitogenic activities of PDGF. Elastase abolished the chemotactic activity of PDGF for fibroblasts but had no effect on its chemotactic activity for monocytes, or on its mitogenic activity...

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