This study investigated the effect of sex hormones on mustard oil (MO)-induced visceral hypersensitivity in female rats and analyzed possible involved signaling pathways. Female rats, either intact or ovariectomized (OVX), were prepared for abdominal muscle electromyography in response to colorectal distension after intracolonic instillation of MO. The effect of MO intracolonic sensitization wa...

conclusions the characteristic features of ige-mediated food allergy are abrupt onset of clinical symptoms, which may result in a life-threatening events, and positive results of the majority of the paraclinical tests that mainly trace the specific ige to foods. moreover, non–ige-mediated food allergies present as chronic diseases and due to lack of proper diagnostic tests the similarity of the...

statement of the problem dental gloves are worn to protect dental care providers from contamination during contact with mucus membranes, blood and saliva. the prevalence of latex allergy has progressively increased due to the widespread use of protective disposable wears, especially latex gloves, among health care workers (hcw) in the past decade. the prevalence of latex allergy among hcw of ir...

Progesterone induces a biphasic Ca(2+) influx and consequent acrosome reaction in human spermatozoa. We have used two procedures to vary the stimulus (dosage and prior receptor desensitization) to investigate the encoding of stimulus strength by intracellular [Ca(2+)] ([Ca(2+)](i)). Acrosome reaction and amplitude (but not kinetics) of the transient [Ca(2+)](i) response (population measurement)...

Based on the patient’s history and clinical features typical of an AIPD [3] , to demonstrate the presence of hypersensitivity to progesterone, we performed patch testing, prick and intradermoreactions with progesterone solubilized in sesame oil as described [2, 3] . All these investigations were performed during the follicular phase to avoid interference with endogenous progesterone. While patc...

Based on the patient’s history and clinical features typical of an AIPD [3] , to demonstrate the presence of hypersensitivity to progesterone, we performed patch testing, prick and intradermoreactions with progesterone solubilized in sesame oil as described [2, 3] . All these investigations were performed during the follicular phase to avoid interference with endogenous progesterone. While patc...

Developmental anomalies of the breast are frequently observed in women. The most serious pathology is gigantomastia. This type of breast hypertrophy may be caused by hypersensitivity of the breast oestrogen and progesterone receptors, by disturbances of the normal balance of oestrogen and androgen hormones, by hyperthyroidism or by hormonal activity of the neoplasm. In most cases gigantomastia ...

Based on the patient’s history and clinical features typical of an AIPD [3] , to demonstrate the presence of hypersensitivity to progesterone, we performed patch testing, prick and intradermoreactions with progesterone solubilized in sesame oil as described [2, 3] . All these investigations were performed during the follicular phase to avoid interference with endogenous progesterone. While patc...