The mammalian reoviruses provide a model for studying specific aspects of the immunopathogenesis of viral infection. We have used two serotype 3 reoviruses to define stages in the pathogenesis of central nervous system (CNS) infection at which a mAb specific for the reoviral cell attachment protein sigma 1 (sigma 1mAbG5) acts to protect mice against lethal disease. sigma 1mAbG5 administered eit...

Let $A$ be a Noetherian ring, $I$ be an ideal of $A$ and $sigma$ be a semi-prime operation, different from the identity map on the set of all ideals of $A$. Results of Essan proved that the sets of associated prime ideals of $sigma(I^n)$, which denoted by $Ass(A/sigma(I^n))$, stabilize to $A_{sigma}(I)$. We give some properties of the sets $S^{sigma}_{n}(I)=Ass(A/sigma(I^n))setminus A_{sigma}(I...

let $g$ be a simple graph‎, ‎and $g^{sigma}$‎ ‎be an oriented graph of $g$ with the orientation ‎$sigma$ and skew-adjacency matrix $s(g^{sigma})$‎. ‎the $k-$th skew spectral‎ ‎moment of $g^{sigma}$‎, ‎denoted by‎ ‎$t_k(g^{sigma})$‎, ‎is defined as $sum_{i=1}^{n}( ‎‎‎lambda_{i})^{k}$‎, ‎where $lambda_{1}‎, ‎lambda_{2},cdots‎, ‎lambda_{n}$ are the eigenvalues of $g^{sigma}$‎. ‎suppose‎ ‎$g^{sigma...

sigma B is a secondary sigma factor of Bacillus subtilis. RNA polymerase containing sigma B transcribes a subset of genes that are expressed after heat shock or the onset of the stationary phase of growth. Three genes (rsbV, rsbW, and rsbX), cotranscribed with the sigma B structural gene (sigB), regulate sigma B-dependent gene expression. RsbW is the primary inhibitor of this system with the ot...

Supplementary Experimental Procedures Isolation, culture, and transfection of primary mammary epithelial organoids Primary mammary epithelial organoids were prepared from 8-week-old CD1 mice (Charles River) as previously described (Nelson et al., 2006). Inguinal glands were removed aseptically, minced with razor blades, and incubated with agitation (350 rpm) at 37°C in DMEM/F12 supplemented wit...

Rothia mucilaginosa is known as a member of commensal bacterial flora in the oral cavity and has received attention as a potential opportunistic pathogen. We previously determined the genomic sequence of R. mucilaginosa DY-18, a clinical strain with biofilm-like structures isolated from an infected root canal of a tooth with persistent apical periodontitis. We found that the DY-18 genome had on...

‎A ring $R$ is strongly clean provided that every element‎ ‎in $R$ is the sum of an idempotent and a unit that commutate‎. ‎Let‎ ‎$T_n(R,sigma)$ be the skew triangular matrix ring over a local‎ ‎ring $R$ where $sigma$ is an endomorphism of $R$‎. ‎We show that‎ ‎$T_2(R,sigma)$ is strongly clean if and only if for any $ain‎ ‎1+J(R)‎, ‎bin J(R)$‎, ‎$l_a-r_{sigma(b)}‎: ‎Rto R$ is surjective‎. ‎Furt...

Thirteen newly isolated monoclonal antibodies (MAbs) were used to study relationships between reovirus outer capsid proteins sigma 3, mu 1c, and lambda 2 (core spike) and the cell attachment protein sigma 1. We focused on sigma 1-associated properties of serotype specificity and hemagglutination (HA). Competition between MAbs revealed two surface epitopes on mu 1c that were highly conserved bet...