THE Bispectral Index (BIS) is increasingly used to monitor the level of (un)consciousness during surgical anesthesia and conscious sedation. Generally, an intraoperative BIS of 40–60 is considered sufficient to maintain adequate hypnosis for surgery. Recently, a new version of the BIS monitor has been introduced: the BIS-XP (Aspect Medical Systems, Newton, MA). The BIS-XP is said to exhibit imp...

Research has established relationships between the personality dimensions of neuroticism and BIS and broad negative emotional reactivity. However, few researchers have examined the relationships among neuroticism, BIS, and discrete negative emotional reactivities. The present study examined whether individuals scoring high on neuroticism and BIS were more reactive across four discrete negative ...

Treatment of 1-(5-acetyl-3,4-dimethythieno[2,3-b]thiophene-2yl)ethanone (1) with dimethylformamide dimethyl acetal afforded enaminone derivative 2, which reacted with amino derivatives to give the corresponding bis-pyrimidine, bis-pyrazole, bis-triazolo-pyrimidine and bis-benzoimidazopyrimidine derivatives.

An earlier computational study (CASPT2/pVDZ) by Winter et al. predicts the 3,5-bis(dimethylamino)benzyl cation to have nearly degenerate singlet and triplet states. Through product studies it is demonstrated that photolysis of 3,5-bis(dimethylamino)benzyl alcohol and its corresponding acetate and phenylacetate esters in alcoholic solvents produces a solvent incorporated adduct, 3,5-bis(dimethyl...

A comprehensive and facile method for the synthesis of new functionalized bis-heterocyclic compounds containing a thieno[2,3-b]thiophene motif is described. The hitherto unknown bis-pyrazolothieno[2,3-b]thiophene derivatives 2a-c, bis-pyridazin othieno[2,3-b]thiophene derivatives 4, bis-pyridinothieno[2,3-b]thiophene derivatives 6a,b, and to an analogous bis-pyridinothieno[2,3-b]thiophene nitri...

Psychopathic individuals are generally unresponsive to motivational and emotional cues that facilitate behavioral regulation. A putative mechanism for this deficiency is Gray’s (1981) behavioral inhibition system (BIS). To evaluate the association between psychopathy and BIS functioning, we administered a laboratory-based assessment of BIS functioning to a group of psychopathic offenders assess...

study of correlation of glasgow coma score and bispectral index in mild and moderate traumatic brain injuries     feizi a [1] , jarineshin h* [2] , estabragnia h [3] , mahoori a [4] , khalkhali h [5] , sattari s [6]     received: 3july, 2011 accepted: 23september, 2011     abstract   background & aims : it is important to monitor the state of consciousness in patients suffering from traumatic b...

UNLABELLED The aim of this study was to analyze the electroclinical features and evolution in patients with benign infantile seizures (BIS) associated with paroxysmal dyskinesia (PD). PATIENTS AND METHODS Among 198 patients with BIS (78 of whom were familial cases), we evaluated 12 unrelated patients with BIS and PD seen at two pediatric neurology departments from January 1990 to February 200...