نتایج جستجو برای: apoptosis assay
تعداد نتایج: 363416 فیلتر نتایج به سال:
Background and Objective: Proliferation and apoptosis of lymphocytes are essential parts of the immune system. Most anti-cancer chemotherapy drugs such as vincristine target cell cycle and induce apoptosis in cancer cells. In other words, dividing cells undergo more apoptosis, which may also include the normal proliferating lymphocytes responsive to malignancies as well. Materials ...
B-acute lymphoblastic leukemia (B-ALL) is the frequent pediatric malignity. Chemotherapy is the most practical approaches to deal with such malignancies. Microtubule-targeted agents are one of the most strategic drugs which formerly use in chemotherapy.Although,colchicine-binding anti-tubulin agents exhibited promising effects in clinical trials, their exact mechanism of action is not fully und...
Abstract: Introduction: Cancer treatment by medicinal plants has long been of interest to researchers. In the meantime, some plant species contain substances which can inhibit or eliminate cancer cells through apoptosis or necrosis. The family of mint and chicory are among the medicinal plants that have many biological effects. The purpose of this study was to investigate the anticancer effec...
Purpose: To investigate the role of dexmedetomidine in gastric ischemia/reperfusion injury using mucosal epithelial cell (GES-1) model.
 Methods: GES-1 were subjected to oxygen-glucose deprivation conditions, followed by increasing concentrations (0.5, 1.0, or 1.5 μM) for 4 h reoxygenation. Cell viability and apoptosis determined 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl-2H-tetrazolium bro...
In this study we examined enhancement effects of Artemisinin plus Glucantime and shark cartilage extract, on promastigotes and amastigotes of L.infantum in in vitro condition.The toxicity of artemisinin, glucantime and shark cartilage extract on the L. infantum promastigotes and amastigote-infected macrophages was evaluated using MTT assay. The role of these drugs in inducing apoptosis in proma...
Background: The SALL4/Sall4 is constitutively expressed in human and mice. SALL4 mRNA could be used as a marker for the diagnosis of different types of cancers. On the other hand, chrysin has diverse biological properties. Objectives: In the present study, the effect of the chrysin was investigated on the CT26 colon cancer in vitro and in vivo. Furthermore, the expression levels of the stem cel...
ICD-85 (venom derived peptides) has anti-proliferative effect and anti-angiogenesis activity on cancer cells. This study was performed to test the effect of ICD-85, on Human breast adenocarcinoma (MCF-7) and normal Human Dermal Fibroblasts (HDF) cell lines. In this experimental study, Mitochondrial activity, Neutral red uptake, Lactate dehydrogenase (cell necrosis), and cell morphology we...
Introduction: It was reported that morphine could induce apoptosis in neurons. However, its specific mechanistic pathways remain elusive. The present study was undertaken to determine whether morphine could induce apoptosis in PC12 cells, a neuronal cell line, and the involvement of Bax and Bcl-2, as upstream factors of mitochondrial pathway. Methods: In an experimental study, the viabili...
Houttuynia cordata Thunb. is an edible and medicinal plant that belongs to the family of Saururaceae widely distributes in Eastern Asia countries. H. have been reported as a promising anticancer agent against various cancer cells. This study was determine anti-proliferative effect extract on gastric cells using vitro experimental model. The cytotoxicity examined via 2,5-diphenyl-2H-tetrazolium ...
OBJECTIVE: The goal of this study was to ferment yoghurt from milk using lactic acid bacteria found in pinecones and examine the cell viability lipid peroxidation levels fermented on Vascular Endothelial Cell Line ECV304.
 METHODS: ECV304 cultured vitro. To determine viability, various concentration yogurt extract with pinecone were given cells MTT Assay. At same doses as Assay, Lipid Pero...
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