Background: TP53 and the oncogene WRAP53 are adjoining genes, producing p53-WRAP53α sense-antisense RNA couples. WRAP53α is indispensable for p53 mRNA regulation and p53 induction following DNA damage. Up-regulated WRAP53β can induce neoplastic transformation and cancer cell survival. All these, along with the associations of WRAP53 single nu...

In surveys of third language acquisition (TLA) research, mixed results demonstrate that there is no consensus among researchers regarding the advantages and/or disadvantages of bilinguality on  TLA.  The  main  concern  of  the  present  study  was,  thus,  to  probe  the  probable  differences between  Persian  monolingual  and  Azeri-Persian  bilingual  learners  of  English  regarding  their...

Background and Objectives: According to the available evidence, consumption of milk and other dairy products among Iranians is far less than recommendations. The share of different milks (i.e., traditionally vs. industrially processed) and its associated variables are, however, neither consistent nor fully known in different Provinces.Materials and Methods: This cross-sectional study was conduc...

Background: In addition to cellular and molecular mechanisms involved in the pathogenesis of asthma, mounting evidences demonstrate that single nucleotide polymorphisms (SNPs) in asthma relevant genes have a role in conferring susceptibility to the disease. CHI3L1 is secreted from macrophages, neutrophils, and airway epithelial cells through an IL-13 related mechanism and contributes to tissue ...

Introduction: Stainless steel alloy used in orthodontics has elements such as iron - magnesium and chromium , which may be released due to corrosion in the mouth . The aim of this study was to evaluate the changes of these elements in the saliva of patients undergoing fixed orthodontic treatment. Methods: In a clinical study with simple non- random sampling , 1ml saliva of 11 patients (7 fem...

Background: Cholesteryl ester transfer protein (CETP) plays a main role in high-density lipoprotein metabolism. CETP gene possesses several single nucleotide polymorphisms which have been associated with plasma high-density lipoprotein cholesterol (HDL-C) concentrations. The aim of this study was to determine the association of CETP -629C/A and I405V polymorphisms with coronary artery disease (...

background: it has been demonstrated that insulin signaling pathway related genes have important roles in polycystic ovary syndrome (pcos) risk. the goal of present investigation was to assess the potential association between insr/nsii (rs2059806) and insr/pmli (rs1799817) snps and pcos. methods: 50 women with pcos and 47 normal controls entered the study. nsii and pmli snps in the insr gene w...

background: the main goal of this study was to conduct a comparative population genetic study of turkish speaking iranian azeris as being the biggest ethno-linguistic community, based on the polymorph markers on y chromosome.  methods: one hundred turkish-speaking azeri males from north-west iran (tabriz, 2008-2009) were selected based on living 3 generations paternally in the same region and n...