Intravascular ultrasound may be useful for studying the natural history of atherosclerotic lesions of different morphologies and for guiding interventional strategies. This study was designed to test the hypothesis that tissue appearance by intravascular ultrasound is related to the biomechanical properties of atheroma components. Forty-three atheroma caps were obtained from the abdominal aorta...

Atomic force microscopy (AFM) cell loading/unloading curves were used to provide comprehensive insights into biomechanical behavior of cardiomyocytes carrying the lamin A/C (LMNA) D192G mutation known to cause defective nuclear wall, myopathy and severe cardiomyopathy. Our results suggested that the LMNA D192G mutation increased maximum nuclear deformation load, nuclear stiffness and fragility ...

Purpose of the study . The aim this work was to effect conservation in various cryoprotectants on biomechanical and morphological properties umbilical cord (UCA) arteries. Materials methods material for 12 arteries, which were divided into 4 groups: (1) native UCA – control without freezing; (2) APC frozen 5 % dextran with addition dimethyl sulfoxide (DMSO) 10 7.5 human serum albumin (HSA); (3)...

Morphometric and stress-strain properties were studied in isolated segments of the thoracic aorta, abdominal aorta, left common carotid artery, left femoral artery, and the left pulmonary artery in 16 male Wistar rats. The mechanical test was performed as a distension experiment where the proximal end of the arterial segment was connected via a tube to the container used for applying pressures ...

background: we presumed that the surgeon himself has an impact on the results after coronary artery bypass grafting (cabg) as there is no unique protocol for the discharge of post-operative cardiac patients at our institution. therefore, we examined whether the surgeon himself has an impact on the intensive care unit (icu) stay of isolated cabg patients. methods: we prospectively studied a tota...

introduction: incidence of sudden cardiac death (scd) has been steadily increasing all over the world. while knowing the cause of scd is one of the favorites of the physicians involved with these cases, it is very difficult and challenging task for the forensic physician. the present report is a prospective study regarding cause of scds on autopsy examination in four-year period, bangalore, ind...

Low patient cooperation erodes many of the proven benefits of antihypertensive therapy. Over the last few years, there have been important advances in our understanding of the nature and management of patient compliance in hypertension and other chronic illnesses. In this article we review the theoretical foundation of compliance behavior; methods of measuring compliance; established and promis...

BACKGROUND Genetic and epigenetic programs regulate dramatic structural changes during cardiac morphogenesis. Concurrent biomechanical forces within the heart created by blood flow and pressure in turn drive downstream cellular, molecular and genetic responses. Thus, a genetic-morphogenetic-biomechanical feedback loop is continually operating to regulate heart development. During the evolution ...