background: breast cancer is the most common cancer in women worldwide. recently, natural remedies such as naringenin (nar) - a kind of flavonoids which can be found in grapefruits, oranges, and tomatoes - seem to be interesting. they play a useful role in treatment and chemoprevention because of having pleiotropic molecular mechanisms of action on breast cancer cells. methods: we performed a p...

to establish a comprehensive picture of the relationship between glutathione s-transferase omega 2 (gsto2; mim: 612314) gene n142d variant (rs. 156697) and breast cancer risk, the present meta-analysis was carried out. studies published up to july 2012 with information about gsto2 polymorphism and breast cancer risk were identified using several electronic databases. we identified 4 eligible st...

background: studies have shown that obese individuals are at increased risk of breast cancer development and poorer prognosis. leptin, an adipose tissue-derived hormone, has pro-inflammatory and proliferative effects and a well-established association with several comorbidities of obesity. this study was designed and conducted to compare the serum levels of leptin in patients with malignant and...

background & aim: breast cancer is recognized as the most common type of cancer among iranian women. cancer screening and early diagnosis are among the most effective strategies to reduce the associated mortality and healthcare costs. accordingly, the aim of this study was to investigate the level of knowledge and practice of breast cancer screening among women referred to hospitals affiliated ...

background : breast cancer (bc) is the most common cancer in iranian women, meanwhile the iranian patients are relatively young. granzyme h (gzmh) is a functional cytotoxic serine protease of nk cell granules, which expands the cell death-inducing repertoire of innate immune system. gzmh is constitutively and highly expressed in human nk cells, in order to possess chymotrypsin-like (chymase) en...

background: baculoviral inhibitor of apoptosis repeat-containing 5 (birc5) gene is an inhibitor of apoptosis that expresses in human embryonic tissues but it is absent in most healthy adult tissues. the copy number of birc5 has been indicated to be highly increased in tumor tissues; however, its association with the age of onset in breast cancer is not well understood. methods: forty tumor tiss...

desmoid tumor of breast is a rare benign, locally aggressive tumor with a high recurrence rate. it has been associated with scar from previous breast surgery or trauma. especially in breast cancer patients with previous operation history, it may simulate recurrent breast cancer clinically and radiologically. we presented multimodality imaging findings (ultrasound, computed tomography, magnetic ...

Background: Researchers suggest that benign breast disease (BBD) is a key risk factor for breast cancer. The present study aimed to determinate the risk level of breast cancer in terms of various BBD subgroups.Methods: A meta-analysis was performed to determinate the risk of breast cancer associated with BBD. Observational studies (traditional case-control studies, nested case-control studies, ...