Vesico-bullous subacute cutaneous lupus erythematosus is an uncommon and severe presentation. The authors report an exuberant case of vesico-bullous subacute cutaneous lupus erythematosus successfully treated with dapsone and hydroxychloroquine.

Currently there is no consensus on the treatment of refractory idiopathic thrombocytopenic purpura (ITP) complicating pregnancy. Our patient with chronic ITP complicating pregnancy, who was refractory to steroids, dapsone, and danazol, was treated successfully with intrapartum splenectomy.

BACKGROUND Treatment of brown recluse spider bites remains controversial; there are multiple options but little evidence of their effectiveness. METHODS Over a 5-year period, family physicians enrolled consecutive patients with suspected brown recluse spider bites. Usual care was provided based on physician preferences. Topical nitroglycerine patches and vitamin C tablets were provided at no ...

The incurable nature, coupled with the myths and mysticisms, kept leprosy away from the main stream of medicine. For similar reasons, public health experts also stayed away, leaving the problems mostly to the social workers and few leprosy specialists. It was the advent of an effective treatment with dapsone and later with MDT that leprosy came to be dealt within the public health terms, with e...

ruptured. She underwent a repeat cesarean delivery because the method of leprosy transmission is not yet proven and to prevent possible vertical transmission to the infant. The patient delivered a female infant weighing 6 lb, 8 oz, with Apgar scores of 8 and 9. On postoperative day 1, Dapsone treatment was restarted; she was given Dapsone, 50 mg daily, and prednisone, 40 mg daily. She was disch...

From 43 Nepalese leprosy patients skin smear negative, and treated with dapsone (diamino diphenyl sulphone), and without any sign of active leprosy or iritis, specimens from iridectomy during cataract surgery were studied histopathologically. Of 49 iris specimens only six (12%) were found to be without any histopathological change. Atrophy of the iris stroma was seen in 63% and neovascularisati...