Infection with equid herpesvirus type 1 (EHV-1) leads to respiratory disease, abortion, and neurologic disorders in horses. Molecular epidemiology studies have demonstrated that a single nucleotide polymorphism resulting in an amino acid variation of the EHV-1 DNA polymerase (N752/D752) is significantly associated with the neuropathogenic potential of naturally occurring strains. To test the hy...

BACKGROUND To date the influence of herpesviruses on the development of equine ocular diseases has not been clearly determined. OBJECTIVE The purpose of this study was to illustrate the course of equine ocular findings over a period of 18 months at 6 month intervals, in correlation with the results of herpesvirus detection. METHODS 266 Lipizzaners in 3 federal states of Austria underwent co...

Neonatal foals respond poorly to conventional vaccines. These vaccines typically target T-helper (Th) cell dependent B-cell activation. However, Th2-cell immunity is impaired in foals during the first three months of life. In contrast, neonatal basophils are potent interleukin-4 (IL-4) producers. The purpose of this study was to develop a novel vaccine triggering the natural capacity of neonata...

В статье представлены современные сведения о герпесвирусах, вызывающих ринопневмонию у лошадей. Приводятся данные клинических проявлениях болезни, методах диагностики и вакцинопрофилактики. Приведены результаты серологических исследований в ИФА поголовья лошадей Алматинской области - найдены антитела как к EHV-1, так EHV-4. Разработанная тест-система для ПЦР позволяет эффективно диагностировать...

The pathogenicity of equine herpesvirus 1 (EHV-1) isolates of Japan were evaluated by using the CBA mouse model. CBA mice were inoculated with eight Japanese EHV-1 strains (89c1, 90c16, 90c18, 97c11, 98c12, 00c19, 01c1 and HH-1) and one British strain (Ab4p). 89c1 caused slight body weight loss and nervous signs in mice at 8 days post infection (dpi). Severe weight loss and nervous signs were o...

Between 2006 and 2008, 5 adult horses hailing from South Germany (4/5 cases) and Austria (1/5) with different case histories but similar lung lesions were investigated at the Faculty of Veterinary Medicine of the Ludwig-Maximilians-University in Munich. Anamnesis included amongst others ongoing respiratory symptoms, weight loss, and poor body condition. Pathological examination of the lungs rev...

Although significant private investment is absorbed in different sectors of power systems, transmission sector is still suffering from appropriate private investment. This is because of the pricing policies of transmission services, tariffs, and especially for investment risks. Investment risks are due to the uncertain behaviour of power systems that discourage investors to invest in the transm...

Equine multinodular pulmonary fibrosis (EMPF) associated with herpesvirus-5 infection (EHV-5), is a severe, fibrosing interstitial lung disease of horses. Most common reported clinical signs are pyrexia, weight loss, depression, respiratory distress tachypnoea and cough. Multiple tissue tropism the EHV-5 has been suggested. Treatment valacyclovir corticosteroids to be successful in few cases, b...