in this study, nystatin liposomal formulation was prepared and characterized. the physicochemical properties of formulations including vesicle size, drug entrapment stability and in vitro release were studied. the highest entrapment efficiency of nystatin into liposomes was obtained about 70% when cholesterol (cho) was added to the formulations prepared with dipalmitoylphosphatidylcholine. in a...

an efficient and cost effective protocol for in vitro propagation of pineapple (ananas comosus var. queen) has been developed. in the proliferation stage, agar based murashige and skoog (ms) media was supplemented with 3.0 mg/l benzyleaminopurine (bap), 0.5 mg/l indole acetic acid (iaa) and 50 mg/l adenine sulphate as rbc design experiment. two approaches were taken to reduce the chemical cost ...

In this study, we propagated two old Galician plum varieties in liquid medium using a temporary immersion system with RITA© bioreactors. Environmental variables including culture system, light intensity, CO2 enrichment, frequency and sucrose supplementation were evaluated relation to vitro proliferation, physiological status ex performance. Bioreactors superior jars for culturing shoots photomi...

Abstract Fructooligosaccharides (FOS) can be used as feed prebiotics, but are limited by high production costs. In this study, low-cost sugarcane molasses was to produce whole-cell biocatalysts containing transfructosylating enzymes Aureobasidium pullulans FRR 5284, followed FOS from using the whole-cells of A. . in molasses-based medium produced cells and broth with a total activity 123.6 U/mL...

BACKGROUND Overflow metabolism is an undesirable characteristic of aerobic cultures of Saccharomyces cerevisiae during biomass-directed processes. It results from elevated sugar consumption rates that cause a high substrate conversion to ethanol and other bi-products, severely affecting cell physiology, bioprocess performance, and biomass yields. Fed-batch culture, where sucrose consumption rat...

BACKGROUND/OBJECTIVES Type 2 diabetes (T2D) is more frequently diagnosed and is characterized by hyperglycemia and insulin resistance. D-Xylose, a sucrase inhibitor, may be useful as a functional sugar complement to inhibit increases in blood glucose levels. The objective of this study was to investigate the anti-diabetic effects of D-xylose both in vitro and stretpozotocin (STZ)-nicotinamide (...

The potential of PLGA-nanoparticles as a carrier of amphotericin B and doxorubicin against visceral leishmaniasis was evaluated by macrophage-mediated drug targeting approach. PLGA-nanoparticles were modified by coating them with macrophage-specific ligand-lectin. Prior to in-vitro studies, characterization studies were carried out systematically include particle size, surface morphology, perce...

Intact air-grown (photosynthetic photon flux density, 400 microeinsteins per square meter per second) clover plants (Trifolium subterraneum L.) were transfered to high CO(2) (4000 microliters CO(2) per liter; photosynthetic photon flux density, 400 microeinsteins per square meter per second) or to high light (340 microliters CO(2) per liter; photosynthetic photon flux density, 800 microeinstein...