Tensor CANDECOMP/PARAFAC (CP) decomposition is a powerful but computationally challenging tool in modern data analytics. In this paper, we show ways of sampling intermediate steps of alternating minimization algorithms for computing low rank tensor CP decompositions, leading to the sparse alternating least squares (SPALS) method. Specifically, we sample the Khatri-Rao product, which arises as a...

FAD-linked oxidases constitute a class of enzymes which catalyze dehydrogenation as a fundamental biochemical reaction, followed by reoxidation of reduced flavin. Here, we present high-resolution crystal structures showing the flavoenzyme 6-hydroxy-l-nicotine oxidase in action. This enzyme was trapped during catalytic degradation of the native substrate in a sequence of discrete reaction states...

Metallo-β-lactamases (MβL) catalyzing the hydrolytic cleavage of the four-membered β-lactam ring in broad spectrum of antibiotics and therefore inactivating the drug; However, the mechanism of these enzymes is still not well understood. Electronic structure and electronic energy of metallo-β-lactamase active center, two inhibitors of this enzyme including penicillin and cephalexin, and differen...

Listening is referred to by many scholars as the most important as well as the most complicated skill in the language, which can cause mental fatigue in the learners. This study was an attempt to investigate the relationship between L2 listening comprehension and listening fatigue among Iranian EFL learners. For this purpose, 86 intermediate and upper-intermediate Iranian EFL learners randomly ...

In this paper we consider a well-known construction due to Gromov and Lawson, Schoen Yau, Gajer, Walsh which allows for the extension of metric positive scalar curvature over trace surgery in codimension at least $3$ is product near boundary. We generalize work $(p,n)$-intermediate $0\leq p\leq n-2$ surgeries $p+3$. then use it well known theorem Carr. Letting ${\cal R}^{s_{p,n}>0}(M)$ denote s...

The human asialoglycoprotein receptor subunit H2a is cotranslationally inserted into the ER membrane. When expressed together with subunit H1 in mouse fibroblasts part forms a hetero-oligomer that is transported to the cell surface, but when expressed alone it is all rapidly degraded. Degradation is insensitive to lysosomotropic agents and the undegraded precursor is last detected in the ER reg...

The motivation behind the idea of product focused process improvement is to make a process improvement program address certain product quality features in an explicit manner. The PROFES methodology [PROFES (2001)] describes such an improvement program through the notion of a PPD (Product-Process Dependency) repository. The typed generic process model (TGPM) [Satpathy (2000)] is a parametric tem...

A well-planned and well-executed new product development (NPD) process, which produces a stream of timely and high quality products, can provide significant competitive advantage to a company. Focusing on product quality as a key measure of NPD performance, we examine the impact of technical and organizational factors on a vehicle development process. Our results indicate that centrality in a p...

The scenario under consideration involves n cascaded continuous processing units responsible for processing m product lines. Each product line needs to be processed by all the units in the same sequence, and has dedicated finite capacity storage tanks before and after every processing unit. A unit can process only one product line at a time. Inputs for all the product lines arrive continuously ...