We measured the effects of slow-release caffeine (SRC) and melatonin (Mlt) on sleep and daytime sleepiness after a seven-time zone eastbound flight. In a double-blind, randomized, placebo-controlled study, each of three groups of nine subjects was given either 300 mg SRC on recovery day 1 (D1) to D5 (0800) or 5 mg Mlt on preflight D-1 (1700), flight day D0 (1600), and from D1 to D3 (2300), or p...

STUDY OBJECTIVES To develop a practical pre-eastward flight treatment to advance circadian rhythms as much as possible but not misalign them with sleep. DESIGN One group had their sleep schedule advanced by 1 hour per day and another by 2 hours per day. SETTING Baseline at home, treatment in lab. PARTICIPANTS Young healthy adults (11 men, 15 women) between the ages of 22 and 36 years. I...

This experimental works summarize the (1), aeroacoustic results of airfoil self-noise generated at Reynolds numbers between 1.0 x 10 and 6.0 x 10. The test facility is a newly built low noise and low flow turbulence open jet wind tunnel, where a NACA0012 airfoil was mounted to the exit nozzle horizontally. The noise measurements were performed at three effective angles of attack at 0.0, 1.4 and...

Flow through mixed flow compressor stage was evaluated theoretically to understand internal flow behaviour. Various shroud configurations in terms of clearance has been considered to see the effect of clearance on compressor performance. The blade to blade relative flow variation from impeller inlet to outlet was evaluated through theoretical analysis. A 3D viscous commercial code Fluent was us...

When administered to humans the pineal honnone me\atonin can phase shift a number of circadian rhythms. This property has prompted the investigation of exogenous melatonin in sleep disorders known to have an underlying chronophysiological basis (i.e. circadian rhythm sleep disorders). Both in field and simulated studies of jet lag and shift work suitably timed melatonin improved sleep and, in s...

Numerical investigation of vortex dynamics in near wake of a hovering hawkmoth and hovering aerodynamics is conducted with a biology-inspired dynamic flight simulator. This simulator is developed to be capable of ‘flying’ an insect on a basis of realistic wing-body morphologies and kinematics. The computed results show a three-dimensional mechanism of vortical structures in hawkmoth hovering. A...

STUDY OBJECTIVES To evaluate the ability of actigraphy compared to polysomnography (PSG) to detect wakefulness in subjects submitted to 3 sleep conditions with different amounts of wakefulness: a nocturnal sleep episode and 2 daytime recovery sleep episodes, one with placebo and one with caffeine. A second objective was to compare the ability of 4 different scoring algorithms (2 threshold algor...