MOTIVATION While the mechanism for regulating alternative splicing is poorly understood, secondary structure has been shown to be integral to this process. Due to their propensity for forming complementary hairpin loops and their elevated mutation rates, tandem repeated sequences have the potential to influence splicing regulation. RESULTS An analysis of human intronic sequences reveals a str...

The study of teachers’ pedagogical knowledge base (PKB) to discover how teachers think and work is attracting increasing attention in ELT. Against this background, the present study aimed at probing the likely variations in EFL teachers’ pedagogical knowledge base as a function of their teaching license status. To this aim, six teachers (two standard-licensed, two alternatively-licensed, and tw...

objective: in all ceramic fixed partial dentures the connector area is a common fracture location. the survival time of three-unit fixed partial dentures may be improved by altering the connector design in regions of maximum tension. the purpose of this study was to determine the effect of buccolingual increase of the connector width on the stress distribution in posterior fixed partial denture...

Recent comparative genomic analysis of alternative splicing has shown that protein modularity is an important criterion for functional alternative splicing events. Exons that are alternatively spliced in multiple organisms are much more likely to be an exact multiple of 3 nt in length, representing a class of "modular" exons that can be inserted or removed from the transcripts without affecting...

The formulation of relativistic hydrodynamics for massive particles with spin 1/2 is shortly reviewed. proposed framework based on the Wigner function treated in a semi-classical approximation or, alternatively, classical treatment 1/2. Several theoretical issues regarding choice energy-momentum and tensors used to construct hydrodynamic are discussed parallel.