نتایج جستجو برای: par index

تعداد نتایج: 441136  

Journal: :Biophysical journal 2008
Filipe Tostevin Martin Howard

At the one-cell stage, the C. elegans embryo becomes polarized along the anterior-posterior axis. The PAR proteins form complementary anterior and posterior domains in a dynamic process driven by cytoskeletal rearrangement. Initially, the PAR proteins are uniformly distributed throughout the embryo. After a cue from fertilization, cortical actomyosin contracts toward the anterior pole. PAR-3/PA...

Journal: :Development 2010
Annita Achilleos Ann M Wehman Jeremy Nance

The apicobasal polarity of epithelial cells is critical for organ morphogenesis and function, and loss of polarity can promote tumorigenesis. Most epithelial cells form when precursor cells receive a polarization cue, develop distinct apical and basolateral domains and assemble junctions near their apical surface. The scaffolding protein PAR-3 regulates epithelial cell polarity, but its cellula...

Journal: :Circulation 1999
C Cicala A Pinto M Bucci R Sorrentino B Walker P Harriot A Cruchley S Kapas G L Howells G Cirino

BACKGROUND The protease-activated receptor-2 (PAR-2) is expressed by vascular endothelial cells and upregulated by lipopolysaccharide (LPS) in vitro. PAR-2 is activated by a tethered ligand created after proteolytic cleavage by trypsin or experimentally by a synthetic agonist peptide (PAR-2AP) corresponding to the new amino terminus of the tethered ligand. METHODS AND RESULTS Intravenous admi...

Journal: :Animal : an international journal of animal bioscience 2012
B T Velayudhan B P Huderson M L McGilliard H Jiang S E Ellis R M Akers

Previous studies in prepubertal heifers suggest that the magnitude of reduction in mammary parenchymal growth in response to ovariectomy varies with the age at which surgery is performed. We hypothesized that ovarian secretions are essential for initiating mammary development but not required to maintain allometric mammary growth in prepubertal dairy heifers. The objectives of this study were t...

پایان نامه :وزارت علوم، تحقیقات و فناوری - دانشگاه فردوسی مشهد - دانشکده ادبیات و علوم انسانی 1393

dans ce mémoire, nous avons concentré notre étude sur la notion d’altérité telle que sartre et beauvoir la définissent à travers leurs essais et plus spécialement dans l’invitée et huis clos. etant donné le rapport étroit qui existe entre les notions existentialistes, la connaissance préliminaire de leur définition, bien que concise, s’est avérée nécessaire avant d’entrer dans notre analyse. c’...

2013
MICHELLY C. PEREIRA SIMONE A. DE BESSA-GARCIA RAVSHAN BURIKHANOV ANA CAROLINA PAVANELLI LOURIVAL ANTUNES VIVEK M. RANGNEKAR MARIA A. NAGAI

Experimental evidence indicates that prostate apoptosis response-4 (Par-4, also known as PAWR) is a key regulator of cancer cell survival and may be a target for cancer-selective targeted therapeutics. Par-4 was first identified in prostate cancer cells undergoing apoptosis. Both intracellular and extracellular Par-4 have been implicated in apoptosis. Relatively little is known about the role o...

Journal: :Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology 2004
Diego Libkind Patricia Pérez Ruben Sommaruga Maria del Carmen Diéguez Marcela Ferraro Silvia Brizzio Horacio Zagarese María van Broock

Twelve yeasts isolated from lakes of Northwestern Patagonia, Argentina, belonging to eight genera (Sporobolomyces, Sporidiobolus, Rhodotorula, Rhodosporidium, Cystofilobasidium, Cryptococcus, Torulaspora, and Candida) were analysed for their ability to produce photoprotective compounds. For this purpose, three laboratory experiments were performed to study the effect of photosynthetically activ...

Journal: :Annals of botany 2003
Jeong Hyun Lee Jan Goudriaan Hugo Challa

The aim of this study was to predict crop growth of year-round cut chrysanthemum (Chrysanthemum morifolium Ramat.) based on an empirical model of potential crop growth rate as a function of daily incident photosynthetically active radiation (PAR, MJ m-2 d-1), using generalized estimated parameters of the expolinear growth equation. For development of the model, chrysanthemum crops were grown in...

Journal: :Journal of drugs in dermatology : JDD 2007
Warren Wallo Judith Nebus James J Leyden

Serine protease inhibitors (soybean trypsin inhibitor [STI] and Bowman-Birk protease inhibitor [BBI]) found in soybeans have been shown to inhibit melanosome phagocytosis by keratinocytes via protease-activated receptor 2 (PAR-2). Pre-clinical studies have confirmed the skin lightening potential of these molecules. In this study, we investigated the efficacy of a novel soy moisturizer containin...

2015
Evan Cavallo

We also defined sequential and parallel versions of the structural operational dynamics, given by judgments e 7→seq e′ and e 7→par e′. These differ on the rules for evaluating pairs: while 7→seq evaluates the first component of a pair before the second, 7→par evaluates the two simultaneously. e1 7→seq e1 〈e1, e2〉 7→seq 〈e1, e2〉 (Pair-S1) e1 val e2 7→seq e2 〈e1, e2〉 7→seq 〈e1, e2〉 (Pair-S2) e1 7...

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