Molecular Science and Biomedicine Laboratory, State Key Laboratory for Chemo/Biosensing and Chemometrics, College of Biology, College of Chemistry and Chemical Engineering, Aptamer Engineering Center of Hunan Province, Hunan University, Changsha, Hunan 410082, China School of Life Sciences, State Key Laboratory of Medical Genetics, Central South University, Changsha, Hunan 410078, China 3 T.D. ...

BACKGROUND Breast cancer is the most common malignancy in Iranian women. Mutations in BRCA1 gene is one of the important genetic predisposing factors in breast cancer. This gene is a tumor suppressor that plays an important role in regulating the functions of RAD51 protein for strand invasion in homologous recombination repair. METHODS The BRCA1 gene has amplified in the DNA isolated from bre...

Dear Editor, The human development index (HDI) is a composite index calculated on the basis of three socioeconomic indicators that reflect three major dimensions of human development: longevity, educational attainment and standard of living to sufficiently capture the multidimensionality of human development. Longevity is measured by life expectancy at birth (LEB); educational attainment is mea...

aedi-Visna is a viral disease of sheep caused by a lentivirus. It is characterized by progressive interstitial pneumonia or meningoencephalitis. Sometimes arthritis, ill-thrift and indurative mastitis are observed. The disease most often progresses slowly, but irreversibly. The disease occurs in all major sheep producing countries with the exception of Australia, New Zealand, and Finland. The i...

Biscogniauxia species are known as fungal trunk pathogens on various tree in the world. During a survey of diseases fruit trees conducted Iran, branch dieback was observed almond Kerman province (in Southeast Iran). Evaluation symptomatic branches revealed wood discoloration cross-sections and presence fruiting bodies an ascomycete fungus their bark. A total 31 isolates were obtained, 13 recove...

BACKGROUND Visceral leishmaniasis (kala-azar) is an endemic disease in some areas of Iran. A cross- sectional study was conducted for sero-epidemiological survey of visceral leishmaniasis (VL) in Baft district from Kerman Province, southeast of Iran. METHODS Blood samples were collected from children up to 12 years old and 10% of adult population from Baft villages with a multi-stage randomiz...

The loss minimization in distribution systems has assumed greater significance recently since the trend towards distribution automation will require the most efficient operating scenario for economic viability variations. To obtain these goals the resources capacity and the installation place are of a crucial importance. In this paper a new method is proposed to find the optimal and simultaneou...

The maternal mortality ratio is an important indicator of socioeconomic conditions in a country or area. This study in Kerman province aimed to compare maternal mortality ratios from different data sources and examine deficiencies in vital data collection in the Islamic Republic of Iran in the context of the Bam earthquake disaster (December 2003). Annual data were collected from documents befo...

On the 26th December 2003 an earthquake with MW=6.5 shook a large area of the Kerman Province in Iran. The epicenter of the devastating earthquake was located near the city of Bam. This paper described the application of differential synthetic aperture radar interferometry (D-INSAR) and ENVISAT ASAR data to map the coseismic surface deformation caused by the Bam earthquake including the interfe...