Quercetin is a typical flavonoid with diverse biological effects, attributable to its free radical scavenging activity. Bioavailability of quercetin aglycone and its glycosides is an important factor for its antioxidant activity in vivo. A severe limitation exists and is imputable to very poor absorption of quercetin when administered orally. To overcome this limitation, development of a value ...

UGT707B1 is a new glucosyltransferase isolated from saffron (Crocus sativus) that localizes to the cytoplasm and the nucleus of stigma and tepal cells. UGT707B1 transcripts were detected in the stigma tissue of all the Crocus species analyzed, but expression analysis of UGT707B1 in tepals revealed its absence in certain species. The analysis of the glucosylated flavonoids present in Crocus tepa...

UNLABELLED BACKGROUND Natural products isolated from plant sources have been demonstrated as potential candidates against several ailments. The scientific investigations on the underlying principles of phytotherapy can pave way for the convergence of traditional medicines and modern science and technologies. RESULTS Quercetin 3-O-(2''-acetyl)-glucoside obtained from ethyl acetate fraction ...

Five minor flavonoid monosides, glycosides of quercetin and kaempferol, together with three previously isolated compounds were identified cochromatographically in P. serotina Ehrh. leaves and flowers (inflorescences) using RP-HPLC and TLC techniques and finally determined as quercetin 3-O-alpha-L-arabinofuranoside (avicularin), 3-O-alpha-L-arabinopyranoside (guaijaverin), 3-O-beta-D-xylopyranos...

Dendritic cells (DCs) play a crucial role in linking innate and adaptive immunity. Thus, DCs have been regarded as a major target of immunosuppressants for the control of harmful immune responses. In this study, we examined the effect of quercetin, a natural flavonoid found in many vegetables and fruits, on the activation and function of mouse DCs. Quercetin effectively inhibited LPS-induced DC...

Sesbaniasesbanhas traditionally been used as astringent, anti-inflammatory, carminative purgative, demulcent and anthelmintic. Phytochemical analysis of the plant showed thepresence of alkaloids, carbohydrates, proteins, phytosterol, phenol, flavonoidsetc.In the present study, an attempt was made to quantify the flavonoid quercetin in the stem extract. TLC was done to confirm the presence of qu...

background tyrosinase is a copper-containing enzyme, which is widely distributed in microorganisms, animals and plants. it is also a key enzyme in melanin biosynthesis, which plays a crucial role in determining the color of mammalian skin and hair. in addition, unfavorable enzymatic browning of plant-derived foods by tyrosinase causes a decrease in nutritional quality and economic loss of food ...

Elevated plasma uric acid concentration is a risk factor for gout, insulin resistance and type 2 diabetes. Quercetin, a flavonoid found in high levels in onions, tea and apples, inhibits xanthine oxidoreductase in vitro, the final step in intracellular uric acid production, indicating that quercetin might be able to lower blood uric acid in humans. We determined the effects of 4 weeks of oral s...