BACKGROUND Whole brain radiotherapy (WBRT) is a vital tool in radiation oncology and beyond, but it can result in adverse health effects such as neurocognitive decline. Hippocampal Avoidance WBRT (HA-WBRT) is a strategy that aims to mitigate the neuro-cognitive side effects of whole brain radiotherapy treatment by sparing the hippocampi while delivering the prescribed dose to the rest of the br...

PURPOSE The purpose of this study was to evaluate patient outcomes in the National Demonstration Project (NDP) of practices' transition to patient-centered medical homes (PCMHs). METHODS In 2006, a total of 36 family practices were randomized to facilitated or self-directed intervention groups. Progress toward the PCMH was measured by independent assessments of how many of 39 predominantly te...

The purpose of this study was to determine whether botulinum toxin A (BTX-A) was efficacious for the treatment of chronic moderate to severe jaw muscle pain in females. This was a randomized double-blind, placebo-controlled crossover trial of BTX-A. Twenty five units injected into each temporalis muscle and 50 U injected into each masseter muscle using three sites per muscle with 0.2 cm per sit...

Objectives: The aim of this study was to identify the role of attentional process in postural control using choice reaction time task while changing the visual and proprioceptive cues under difficult balance task (standing on one-leg). Methods: This cross-sectional study was conducted by participating 20 young people (22.75±2.29). Each subject performed one-leg standing as balance task for e...

Long non-coding RNAs (lncRNAs) have shown great potential as powerful and non-invasive tumor markers. However, little is known about their value as biomarkers in pancreatic cancer (PC). We applied an Arraystar Human LncRNA Microarray which targeting 7419 lncRNAs to determine the lncRNA expression profile in PC and to screen the potential biomarkers. The most increased lncRNAs in PC tissues were...

BACKGROUND This meta-analysis aimed to evaluate the efficiency and safety of transcutaneous electrical nerve stimulation (TENS) for pain control after total knee arthroplasty. METHODS A systematic search was performed in Medline (1966 to June 2017), PubMed (1966 to June 2017), Embase (1980 to June 2017), ScienceDirect (1985 to June 2017), and the Cochrane Library. Only randomized controlled t...

OBJECTIVE To estimate the rate of success and risk of maternal morbidities in women with three or more prior caesareans who attempt vaginal birth after caesarean (VBAC). DESIGN Retrospective cohort design. SETTING Multicentre, from 1996 to 2000, including 17 tertiary and community delivery centres in north-eastern USA. POPULATION A total of 25 005 women who had had at least one prior caes...

HYPOTHESES Task performance improves with the use of a balanced degree of shadow and illumination compared with no or maximum shadow contrast; and overhead shadow-casting illumination is better than side illumination. DESIGN The standard task entailed touching target points on an undulating surface by using a surgical hook. Each run consisted of 13 target points in a random sequence. Five set...