Sustained high levels of circulating catecholamines may induce cardiotoxicity through oxidative mechanisms. Isoproterenol is a synthetic catecholamine with increasing attention owing to this application in cardiology. The aim of the present study was to investigate the cardioprotective effects of Vitis vinifera seed against isoproterenolinduced myocardial ischemia. Normal Wistar strain rats wer...

Dietary stilbenoids are receiving increasing attention due to their potential health benefits. However, most studies concerning the bioactivity of stilbenoids were conducted with pure compounds, for example, resveratrol. The aim of this study was to characterize a complex root extract of Vitis vinifera in terms of its free radical scavenging and cellular antioxidant and anti-inflammatory proper...

Grapevines exhibit a wide spectrum of resistance to the powdery mildew fungus (PM), Erysiphe necator (Schw.) Burr., but little is known about the transcriptional basis of the defense to PM. Our microscopic observations showed that PM produced less hyphal growth and induced more brown-colored epidermal cells on leaves of PM-resistant Vitis aestivalis 'Norton' than on leaves of PM-susceptible Vit...

To investigate the hepatoprotective potential of ethanolinc grape seed extract on acetaminophen (APAP) induced liver toxicity in wistar rats. Silymarin was used as reference hepatoprotective agent. Liver injury was induced by APAP (2 gm/kg body weight, bw) on the 1st day of experiment. Vitis vinifera (V. vinifera)L seed extract (200 and 400 mg/kg bw) and silymarin (100 mg/ kg bw) was administer...

The aerial parts of Vitis vinifera Linn. (Common grape, Hindi ⎯ Angur) have been widely used in Ayurveda to treat a variety of common and stress related disorders. The seed extract of grapes was evaluated by Sreemantula and others for antistress activity in normal and stress induced rats. Furthermore, the extract was studied for nootropic activity in rats and in vitro antioxidant potential to c...

Grapevine (Vitis vinifera L [...]