نتایج جستجو برای: ژن pvl

تعداد نتایج: 17054  

Journal: :Proceedings of the National Academy of Sciences of the United States of America 2010
Pauline Yoong Gerald B Pier

Community-acquired infections caused by methicillin-resistant Staphylococcus aureus (MRSA) expressing the Panton-Valentine leukocidin (PVL) are rampant, but the contribution of PVL to bacterial virulence remains controversial. While PVL is usually viewed as a cytotoxin, at sublytic amounts it activates protective innate immune responses. A leukotoxic effect might predominate in high inoculum st...

Objective(s): Coronary artery disease (CAD) is known as a life threatening disease, worldwide. In this study the role of HTLV-1 infection was evaluated on cardiac involvement in an endemic region of northeastern Iran.Materials and Methods: Serologic and molecular tests for HTLV-1 infection were carried out in subjects who had coronary an...

Journal: :Journal of clinical microbiology 2012
Kome Otokunefor Tim Sloan Angela M Kearns Richard James

Limited comprehensive molecular typing data exist currently for Panton-Valentine leucocidin (PVL)-positive, methicillin-sensitive Staphylococcus aureus (PVL-MSSA) clinical isolates. Characterization of PVL-MSSA isolates by multilocus sequence typing (MLST) and spa typing in this study showed a genetic similarity to PVL-positive, methicillin-resistant S. aureus (PVL-MRSA) strains, although three...

Journal: :Journal of clinical microbiology 2010
Cedric Badiou Oana Dumitrescu Narelle George Andrea R N Forbes Eleanna Drougka Kian Sing Chan Nadjia Ramdani-Bouguessa Helene Meugnier Michele Bes Francois Vandenesch Jerome Etienne Li Yang Hsu Mohamed Tazir Iris Spiliopoulou Graeme R Nimmo Kristina G Hulten Gerard Lina

Staphylococcus aureus strains producing Panton-Valentine leukocidin (PVL) have been epidemiologically linked to specific human infections. To evaluate immunological tests that may be used to diagnose infections with PVL-producing strains, we prospectively collected pus, respiratory tract specimens, and joint fluid specimens from which S. aureus had been isolated in clinical laboratories in six ...

Journal: :Journal of interventional cardiology 2003
Jean-François Piéchaud

Paravalvular leak (PVL) is a complication observed in patients after prosthetic valve replacement. The incidence of PVL is estimated as 2-3%. The cause of PVL may be paravalvular infection, suture continuity disruption, damage of tissues around the annulus or limitation of disc mobility by thrombus or vegetation. The preferable method of treatment of PVL is surgery. Recently, percutaneous closu...

2015
Peter Boan Hui-Leen Tan Julie Pearson Geoffrey Coombs Christopher H Heath James Owen Robinson

BACKGROUND Panton Valentine Leukocidin (PVL) has been associated with invasive Staphylococcus aureus soft tissue and pneumonic infections. METHODS From September 2007 to January 2009 at Royal Perth Hospital we tested for the PVL gene in S. aureus isolates from an invasive site, a suspected PVL-related soft tissue infection and all MRSA isolates. We could access medical records for 141 PVL pos...

2016
Dharm R. Bhatta Lina M. Cavaco Gopal Nath Kush Kumar Abhishek Gaur Shishir Gokhale Dwij R. Bhatta

BACKGROUND Methicillin resistant Staphylococcus aureus (MRSA) is a major human pathogen associated with nosocomial and community infections. Panton Valentine leukocidin (PVL) is considered one of the important virulence factors of S. aureus responsible for destruction of white blood cells, necrosis and apoptosis and as a marker of community acquired MRSA. This study was aimed to determine the p...

2014
RUI XU YU-FENG YUAN AHMET AYAV CHONG-QING JIANG LAURENT BRESLER ZHI-SU LIU NGUYEN TRAN

The aim of the present study was to investigate the effect of portal vein ligation (PVL) on the tumor growth rate and liver regeneration in rat cirrhotic liver lobes. A total of 45 male Wistar rats were randomly divided into PVL, hepatic tumor (HT) and HT + PVL groups (n=15 per group). Liver regeneration and tumor growth in ligated and non-ligated lobes were evaluated prior to and following PVL...

Journal: :Pediatrics and neonatology 2008
Biserka Resić Maja Tomasović Radenka Kuzmanić-Samija Marin Lozić Jasminka Resić Mirsala Solak

The purpose of this study was to question the correlation of different grades of periventricular leukomalacia (PVL) and subsequent neurodevelopmental outcome. In a prospective study we followed 52 preterm infants. Infants were divided into three groups according to their cranial ultrasound findings of PVL (De Vries classification). Seventeen children had PVL 1, 20 children had PVL 2, and 15 chi...

Journal: :The Journal of infectious diseases 2010
Steven Y C Tong Rachael A Lilliebridge Emma J Bishop Allen C Cheng Deborah C Holt Malcolm I McDonald Philip M Giffard Bart J Currie Craig S Boutlis

BACKGROUND Regional differences in the prevalence of Panton-Valentine leukocidin (PVL) and PVL isoform-harboring strains as well as in the local population structure of Staphylococcus aureus may influence the clinical spectrum of S. aureus infections. METHODS Using a prospective collection of S. aureus isolates from northern Australia, we determined differences between infections caused by (1...

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