Alman ceza hukukunda intihar etmek suç değildir. Suç olmayan bir eyleme iştirak edenler de hukukundaki bağlılık kuralı gereğince cezalandırılamaz. Ancak kamuoyunda ve bilim çevrelerinde intihara yardım niteliğindeki bazı eylemlerin cezalandırılması gerektiği konusu, yoğun olarak tartışılmaktadır. Bu tartışmalar neticesinde 2015 yılında, belli eylemler Ceza Kanunu’nun 217. paragrafı ile cezai ya...

This edition of the Journal starts with the big questions in psychiatry: what is a diagnosis? And how does one justify treatment against the will of the individual? The next version of the World Health Organization’s bible, the ICD–11, is being prepared at the same time as the American Psychiatric Association’s fifth edition of the DSM. The push for harmonising these two different systems is di...

PURPOSE Human papillomavirus (HPV) type-16 has been associated with invasive squamous cell carcinoma of the head and neck. This study examines the role of HPV-16 in the progression of oral head and neck cancer by determining the quantity of HPV-16 DNA in premalignant and malignant lesions, using real-time quantitative PCR, to more accurately determine the role of HPV-16 in oral head and neck sq...

Gene identification represents the first step to a better understanding of the physiological role of the underlying protein and disease pathways, which in turn serves as a starting point for developing therapeutic interventions. Familial hypercholesterolemia is a hereditary metabolic disorder characterized by high low-density lipoprotein cholesterol levels. Hypercholesterolemia is a quantitativ...

The purpose of the present study was to validate the quantitative culture and cellularity of bronchoalveolar lavage (BAL) for the diagnosis of ventilator-associated pneumonia (VAP). A prospective validation test trial was carried out between 1992 and 1997 in a general adult intensive care unit of a teaching hospital. Thirty-seven patients on mechanical ventilation with suspected VAP who died at...

BACKGROUND As CDK-16 has been shown to be upregulated in several transformed cancer lines, we hypothesized that the cyclin-dependent kinase 16 (CDK-16) may be upregulated in serous epithelial ovarian cancer (EOC) cells. Therefore, we comparatively examined the mRNA and protein expression of CDK-16 in samples resected from serous EOC patients and normal controls. MATERIAL AND METHODS Tissue sa...