OBJECTIVE To determine the duration of protection from hepatitis B vaccine given in infancy and early childhood. DESIGN Cross sectional serological study of hepatitis B virus infection in children of various ages 14 years after the start of a trial of vaccination regimens. SETTING Two villages in the Gambia. PARTICIPANTS Children and adolescents given hepatitis B vaccine in infancy or ear...

OBJECTIVE Distributions of serum concentrations of insulin among adolescents and young adults are poorly understood in the U.S. The objective of this study was to describe the distribution of serum insulin across demographic characteristics of U.S. adolescents and young adults. RESEARCH DESIGN AND METHODS A total of 1,791 male and female subjects aged 12-19 years who participated in the Natio...

PURPOSE We report on the prevalence of benign prostatic hyperplasia (BPH) and lower urinary tract symptoms (LUTS) among men of Jeju Island, representing a coastal and insular area, using a cross-sectional community-based survey. MATERIALS AND METHODS A total of 553 participants in a prostate health screening campaign on Jeju Island were subjected to measurements of the International Prostate ...

Changes in executive functions have been found in older adults and also in young adults experiencing positive or negative mood states. The current study investigated the hypothesis that older adults would show greater executive function impairment following mood induction than young adults. Ninety-six participants (half aged 19-37, half aged 53-80) completed a neutral, positive, or negative moo...

PURPOSE This study examined the effects of daily physical activity level on health-related factors according to gender and identified age-specific differences among Korean adults. METHODS Using data from the Korea National Health and Nutrition Examination Survey VI (2014-2015), we selected adults aged 19-64 years who participated in both a health examination and health interview survey. The s...

INTRODUCTION Data on the thyroid function of a randomly chosen elderly population was collected during a multicentre study performed in Poland (PolSenior) in 2007-2010. MATERIAL AND METHODS The population of 4,190 participants under study was divided into six age subgroups of > 65 to > 90 years of age and a younger group aged between 55 and 59 years. Assessment of thyroid function was based o...

BACKGROUND Living alone, a proxy for social support, has been inconsistently linked with cardiovascular risk. METHODS We investigated whether living alone was associated with increased mortality and cardiovascular risk in the global REduction of Atherothrombosis for Continued Health (REACH) Registry. Stable outpatients at risk of or with atherothrombosis were recruited from December 1, 2003, ...

OBJECTIVE To examine functional connectivity within the basal ganglia network (BGN) in a group of cognitively normal patients with early Parkinson disease (PD) on and off medication compared to age- and sex-matched healthy controls (HC), and to validate the findings in a separate cohort of participants with PD. METHODS Participants were scanned with resting-state fMRI (RS-fMRI) at 3T field st...