نتایج جستجو برای: 85 peptide
تعداد نتایج: 245786 فیلتر نتایج به سال:
The stimulatory activity of peptides from the alpha 1 domain of the major histocompatibility complex (MHC) class I antigen on adipose cell glucose transport was previously shown to require a preformed, ordered conformation of the peptide. The two peptides studied previously were Dk-(61-85) (ERETQIAKGNEQSFRVDLRTLLRYY) and Dk-(69-85). We now show that systematic alanine substitution in Dk-(69-85)...
HLA-DR2 is associated with susceptibility to multiple sclerosis (MS). A peptide from human myelin basic protein (MBP, residues 85-99) was previously found to bind to purified HLA-DR2 (DRA, DRB1*1501) and to be recognized by human MBP-specific T cell clones. Soluble HLA-DR2 was expressed in the baculovirus system by replacing the hydrophobic transmembrane regions and cytoplasmic segments of DRal...
In the course of a screening program for novel antibiotics showing antitumor activity, a cyclic peptide antibiotic sohbumycin was isolated from the culture broth of Streptomyces sp. No. 82-85, which had been isolated from a soil sample collected in Kanagawa prefecture, Japan. The isolation and physico-chemical properties of sohbumycin and fermentation and taxonomy of the producing organism, Str...
Susceptibility to multiple sclerosis (MS) is associated with the human histocompatibility leukocyte antigen (HLA)-DR2 haplotype, suggesting that major histocompatibility complex class II-restricted presentation of central nervous system-derived antigens is important in the disease process. Antibodies specific for defined HLA-DR2-peptide complexes may therefore be valuable tools for studying ant...
گلوتامین مهمترین و غالبترین اسیدآمینه موجوددرخون میباشدکه یک منبع آمینواسیدی آزاددرعضلات اسکلتی بوده و در بدن به عنوان منبع مهم انرژی عمل می کند.در تمرینات شدیدو طولانی مدت سطح گلوتامین پلاسما کاهش می یابدو نشانه هایی از تغییرات در متابولیسم گلوکز و هورمونهای متابولیکی مربوطه مشاهده می گردد که میتواند باعث ضعف,خستگی و نهایتاتحلیل عضلانی در ورزشکاران شود.جهت بررسی تاثیر مصرف مکمل گلوتامین بر سطح...
Multiple sclerosis (MS) is a chronic debilitating disease affecting the central nervous system (CNS) in humans. Experimental autoimmune encephalomyelitis (EAE) remains the primary animal model of MS. MS/EAE are considered to be autoimmune diseases mediated by CD4 T helper (TH) cells. The role of B cells and antibody is under debate. Previous studies established B cell dependent (induced with re...
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