This study aimed to investigate the anti-angiogenic activity of Vitex agnus castus methanol extract in vivo. Eggs were incubated for three days, small whole made on the fine pinpoint, next day the egg’s sac penetrated and a small frame was made in the shell. The window was resealed and eggs were returned to the incubator until day 10 of chick embryo development, 20 µl of 500mg/ml of the methano...

Introduction: PCOS is an important reproductive and endocrine disorder in women in the reproductive age. Present reports indicate that Vitex agnus-castus acts through hypothalamus-pituitary axis. This study was carried out to evaluate the effects of Vitex fruit hydroalcoholic extract on the alteration of sex hormones in a PCOS animal model. Methods: Following 14 days of monitoring of estrous...

Retinal pathologic angiogenesis is the leading cause of blindness in human generate from age-relatedmacular degeneration (AMD), diabetic retinopathy and premature (ROP).The aim this studyis to investigate effect vitex agnus castus leave extract on induced retinal rabbitsby intravitreal injection VEGF. Alcoholic prepared formulated forintravitreal injection. Twenty four pigmented rabbits include...

Vitex agnus-castus (VAC) is a plant that has recently been used to treat the symptoms of menopause, by its actions on the central nervous system. However, little is known about its actions on disturbances in lipid metabolism and nonalcoholic fat liver disease (NAFLD), frequently associated with menopause. Ovariectomized (OVX) rats exhibit increased adiposity and NAFLD 13 weeks after ovary remov...

D-galactose induces pancreatic disorder along with aging mouse model. Vitex agnus-castus (VAC) has potential pancreatic protective effect. Hence, this study was designed to evaluate the hypoglycemic and pancreas protective effects of VAC hydroalcoholic extract in D-galactose-induced aging female mice. In the present experimental study, 72 adult female Naval Medical Research Institute (NMRI) mic...

Growth and nutrient uptake of seven tree species were evaluated with the goal of selecting the species that can be used for wastewater enhancement by dendro-purification, or green tree filtering, and for restoration of riparian woodlands. Trees were grown in pots with an inert mixture of perlite and vermiculite and irrigated with either nutrient solution or treated wastewater We measured the ef...

According to their accessibility and lower cost-effectiveness when compared synthetic chemical treatments, medicinal wild plants herbs have been used for ages as beneficial tools in the management of many diseases. The popular plant Vitex agnus-castus, which is indigenous Mediterranean region widely distributed Europe, Asia, North Africa, treat a number conditions diseases, including premenstru...

Background: Cadmium toxicity is an environmental health menace in developing countries, which can result damage to the male reproductive system. The mechanisms of cadmium include increase lipid peroxidation, depletion glutathione, reduction protein-bound sulfhydryl groups, and oxidative stress. Agnus castus has been differently reported for its strong antioxidant potential reproductive-enhancin...

In present study the effects of anti-inflammatory and antinociceptive of vitex hydro-alcoholic extract were evaluated on male mice. In inflammatory test mice were divided into 7 groups: first group was control. The second group, positive control group, received dexamethasone (15 mg/kg) and the other five groups received different doses of hydroalcohol extract of Vitex fruit (265, 365, 465, 565,...