One inevitable consequence of aging is the gradual deterioration physical function and exercise capacity, driven in part by adverse effect age on muscle tissue. We hypothesized that relationships exist between age-related differentially expressed genes (DEGs) skeletal age-associated declines capacity. Previously, male C57BL/6mice (6m, months old, 24m, 28m) were tested for using a composite scor...

Diarrheal diseases still remain health problem worldwide and out of many bacteria responsible for, Shigella and pathogenic Escherichia cause the most diarrheas in the world. Shigellacause bacterial dysenteries and shigellosis through invasion where the most effective proteins for pathogenesis is Ipac. Critical virulence protein for ETEC infection is CFA/I with two subunits called cfab and cfae....

Enterotoxigenic Escherichia coli (ETEC), a major global cause of diarrhea, initiates the pathogenic process via fimbriae-mediated attachment to the small intestinal epithelium. A common prototypic ETEC fimbria, colonization factor antigen I (CFA/I), consists of a tip-localized minor adhesive subunit CfaE and the stalk-forming major subunit CfaB, both of which are necessary for fimbrial assembly...

shigella and escherichia belong to the enterobacteriaceae family which are the cause for most of the diarrheal cases in the world. shigella can cause bacterial dysenteries and shigellosis. one of the most effective proteins for pathogenesis is invasion plasmid antigen c (ipac). other bacteria like enterotoxogenic (etec), enterohemorrhagic (ehec), and e.coli can also cause diarrhea and produce i...