Artemisia species, growing in almost all the northern hemisphere, is used in folk medicine of some countries as a remedy for hypertension. Since some cardiovascular disorders including hypertension are accompanied with altered responsiveness of vascular alpha-adrenergic receptors, the effect of aqueous Artemisia annua extract (100 and 200 mg kg-1) on a1-adrenoceptor agonist-induced contraction ...

Angiotensin II is a major endocrine hormone that affects directly both vascular smooth muscle and endothelial cells. Since vascular reactivity to angiotensin II changes in more physiological and pathophysiological conditions, the present study was performed to investigate the effect of intraperitoneal administration of angiotensin-converting enzyme inhibitor and captopril (30 and 50 mg kg-1, on...

considering the anti-diabetic potential of trigonella foenum-graecum (tfg) and its beneficial effect on aortic reactivity of diabetic rats, this study was conducted to evaluate the effect of its alcoholic seed extract on aortic reactivity and also figure out mechanisms including the role of adrenergic and angiotensinergic systems in streptozotocin-diabetic rats. male wistar rats were divided in...

angiotensin-converting enzyme (ace) inhibitors including quinapril could exert a protective effect on cardiovascular system through endothelial system in normoglycemic and diabetic rats. the present experimental work was designed to study the vascular reactivity of aortic ring segments isolated from streptozotocin (stz)-diabetic rats treated for 4 weeks with nitro-l-arginine-methyl ester (l-nam...

Stress fibres form a fully integrated meshwork with the submembranous contractile actin cortex that generates and propagates traction forces across entire cell.

Xenopus oocytes assemble an array of F-actin and myosin 2 around plasma membrane wounds. We analyzed this process in living oocytes using confocal time-lapse (four-dimensional) microscopy. Closure of wounds requires assembly and contraction of a classic "contractile ring" composed of F-actin and myosin 2. However, this ring works in concert with a 5-10-microm wide "zone" of localized actin and ...

Perfect graphs form one of the distinguished classes finite simple graphs. In 2006, Chudnovsky, Robertson, Seymour and Thomas proved that a graph is perfect if only it has no odd holes antiholes as induced subgraphs, which was conjectured by Berge. We consider class ${\mathcal A}$ have holes, stretchers subgraphs. particular, every belonging to perfect. Everett Reed belongs perfectly contractil...