نتایج جستجو برای: contractile
تعداد نتایج: 21721 فیلتر نتایج به سال:
Although cisplatin is one of the most effective cancer drugs which is widely used in the treatment of various neoplasms, its side effects, especially vomiting may limit its use. It has been demonstrated that cytotoxic drugs lead to a sudden release of serotonin (5-HT). The following study was performed to determine the possible interactions of cisplatin with 5-HT receptors. In this study, the...
Background & Objective: Regarding growing incidence of atherosclerosis and cardiovascular diseases in diabetes mellitus, the effect of oral intake of Marrubium vulgare (MV) shoots on contractile response of isolated aorta was investigated in rats for two months in Tehran during 2003. Materials & Methods: In this experimental study 44 male wistar rats were randomly divided into control, MV-treat...
results the bacteriophage, designated mj1, was isolated by testing against a clinical mdr e. coli 3 strain. the mj1 phage showed a wide range of heat and ph stability. the phage morphology, determined by transmission electron microscopy, revealed a structure comprised of a head (108 ± 0.2 nm long by 128 ± 0.5 nm wide) and a contractile tail (123 ± 0.5 nm long by 15 - 26 nm wide). these features...
Background & Aims: Considering increasing incidence of cardiovascular disorders in diabetes mellitus and some evidence on antioxidant and antidiabetic potentials of naringenin, this study was conducted to evaluate the beneficial effects of 6-week administration of naringenin on contractile reactivity of isolated thoracic aorta in diabetic rats. Methods: Male Wistar rats were divided into contro...
It has been reported that some of H1 receptor antagonists have important effects on cardiovascular system. Terfenadine as a non-sedative H1 receptor antagonist has an arrhythmogenic activity. In this study we have shown the effects of four antihistamine drugs: terfenadine, loratadine, clemastine and diphenhydramine, on the rate and contractions of isolated rat atria. Terfenadine (1-10 µM) cause...
Introduction & Objective: Vascular complications represent the main cause of mortality in diabetic patients. Considering the role of plants containing flavonoids in elimination of diabetic vascular disorders and the protective effect of the aqueous extract of Artemisia annua on aortic contractile response in diabetic rats, we evaluated the mechanism of vasodilating action of Artemisia annua ext...
Introduction & Objective : Considering the higher incidence of atherosclerosis and cardiovascular disorders in diabetes mellitus, this study was conducted to evaluate the effect of oral one-month administration of red pepper (Capsicum frutescens) on the contractile reactivity of isolated aorta in diabetic rats. Materials & Methods : For this purpose, male Wistar rats(n=32) were randomly divi...
Background and Objective: Considering the higher incidence of atherosclerosis and cardiovascular disorders in diabetes mellitus, this study was conducted to evaluate the beneficial effect of oral 6-week administration of Cynara scolymus L. (CS) on contractile reactivity of isolated thoracic aorta. Materials and Methods: Wistar rats were divided into control, CS-treated control, diabetic, and C...
Background & Objective : Food restriction has a protective effect against damaging agents and prevents cardiovascular disorders. This study was conducted to evaluate the effect of food restriction on contractile reactivity of male rats using isolated tissue setup. Materials & Methods: Male Wistar rats were randomly divided into one control and three experimental groups. Control group receive...
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