نتایج جستجو برای: dr molecule and peripheral blood mononuclear cell pbmc proliferation
تعداد نتایج: 17243511 فیلتر نتایج به سال:
background: atherosclerosis, a chronic inflammatory disease of the vessel wall is characterized by local and systemic immune responses to a variety of antigens. oxidized low-density lipoprotein (oxldl) is considered as an important determining factor in the pathogenesis of atherosclerosis. objective: the purpose of this study was to investigate the degree of peripheral blood mononuclear cells (...
Background and purpose: Peroxisome proliferation-activated receptors (PPARγ) are a class of ligand-dependent nuclear receptors, which act as transcription factors. In fact, the increased activity of PPARγ, can increase the expression and secretion of adiponectin but in patients with coronary artery disease these levels are reduced. This study was conducted to investigate the effect ...
Background: The appendix is considered as part of the gut-associated lymphoid tissue; however, lymphocyte subsets in this tissue are not fully defined. Objective: To investigate and compare the function and phenotype of lymphocyte subsets in peripheral blood and appendix of patients with normal and inflamed appendix tissues. Methods: Peripheral blood samples and appendiceal mononuclear cells we...
Objective It has long been known that chickens, like mammals, are capable of producing antigen-specific immunoglobulin Y (IgY), which functions similar to IgG. The present study was performed to investigate the activity of IgY anti-Mycobacterium tuberculosis on proliferation, interleukin (IL)-2, and interferon (IFN)-γ expression of rat peripheral blood mononuclear cells (PBMCs). Materials and...
Within the normal human epidermis only Langerhans and indeterminate cells express HLA-DR. Human keratinocytes (HK), however, may also express HLA-DR in certain disease states characterized by mononuclear cell infiltrates. Previous studies have shown that HK synthesize HLA-DR in response to stimulation by interferon gamma (INF-gamma). The purposes of this study were to define conditions under wh...
conclusions in conclusion, occult hbv was found in 36% of patients with negative results for hbsag, but positive results for hcv. detection of hbv-dna in both pbmcs and plasma together in comparison with plasma alone provided more true identification of obi.the svr rate was significantly higher in coinfected patients than mono-infected ones. background occult hepatitis b virus (hbv) infection (...
Background & Aim: Peripheral Blood Mononuclear Cells (PBMCs) are the main components of the immune system, including lymphocytes and monocytes. These cells are being used in most immunological studies and therefore, isolation, culture and transfection of these cells are of great importance. The transfection of these cells is currently a key concern; this is because most common methods of transf...
Natural Killer (NK) cells are the main lymphocyte population expressing P75 B chain of the IL-2 receptor (IL-2R). Consequently, incubation of peripheral blood lymphocytes with IL-2 induce selective activation of NK cells and results in NK activity and generation of Lymphokine activated killer (LAK) cells activity and proliferation. One of the early events during IL-2 activation of peripheral bl...
Little information is available on the specific role of alveolar macrophages (AMs) in modulating local cellular reactions to inhaled allergens in atopic asthma. We investigated the influence of alveolar macrophages obtained by bronchoalveolar lavage (BAL) on the proliferative responses of lavage and peripheral lymphocytes from 12 patients with atopic asthma, 6 nonasthmatic symptomatic atopic su...
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