of ill vitro release testing as a QA tool to ensure batch-to-batch uniformity has been gaining both increasing popularity and contempt in the pharmaceutical industry. Regardless of views and opinions, it is worthwhile to be prepared to conduct such studies if necessary. Currently, the most publicized methods use horizontal ("Franz or Modified Franz") diffusion cells, with an artificial support ...

conclusions this study demonstrated that physicochemical properties, in vitro release and rat intestine permeability were dependent upon the contents of s/c, water and oil percentage in formulations. background self-emulsifying drug delivery system is an isotropic mixture of natural or synthetic oils, non-ionic surfactants or, one or more hydrophilic solvent and co-solvents/surfactant and polym...

Using Ephestia kuehniella larvae as hosts, invert emulsion (IE) and an aqueous suspension (AS) of Beauveria bassiana (isolate IR34-JS2) and Metarhizium anisopliae (isolate IR41-TT1) formulations were compared when stored for three months at either 3 °C or 25 °C. Initially, IE formulations of isolates JS2 and TT1 were 13- and 14-fold more virulent than AS formulations, based on their LC50 values...

  The immunogenicity of ten different formulations of intranasal diphtheria and tetanus vaccines which containing different absorption enhancers, adjuvants and other excipients were determined in guinea pigs by the serum neutralization (SN) method. From these ten formulations, it was selected four formulations which gave significant immunogenicity in guinea pigs. In order to design the "final f...

Objective(s): In the current study, sunscreen and moisturizing properties of solid lipid nanoparticle (SLN)-safranal formulations were evaluated. Materials and Methods:Series of SLN were prepared using glyceryl monostearate, Tween 80 and different amounts of safranal by high shear homogenization, and ultrasound and high-pressure homogenization (HPH) methods. SLN formulations were characterized ...

The present study aimed to investigate two numerical solutions of the Navier-Stokes equations. For this purpose, the mentioned flow equations were written in two different formulations, namely (i) velocity-pressure and (ii) vorticity-stream function formulations. Solution algorithms and boundary conditions were presented for both formulations and the efficiency of each formulation was investiga...

Objective(s): The present study aimed to determine and compare moisturizing and occlusion effects of different solid lipid nanoparticles (SLN) and nanostructured lipid carriers (NLC) using magnetized water and deionized water.Materials and Methods: SLN formulations were prepared using various lipids, including Tripalmitin, Compritol®, Pr...