Background: Some early staged NSCLC appears as non-subpleural peripheral pulmonary nodules. Thoracic surgeons usually adopt extended wedge resection or segmentectomy to remove these Video-assisted thoracoscopic surgery (VATS) has been carried out extensively worldwide in lung surgeries. The purpose of this study was evaluate changes postoperative function after undergoing VATS and anatomical ‏r...

BACKGROUND Obesity reduces FVC, the most commonly used measurement of vital capacity (VC) and slow VC (SVC). It is unknown whether the difference between SVC and FVC is constant in different body mass indices (BMIs). We hypothesized that the difference between SVC and FVC increases as a function of BMI. METHODS We retrospectively reviewed pulmonary function tests (PFTs) that included spiromet...

OBJECTIVES To develop mean and 95% confidence limits for the lower limit of normal (LLN) values for forced expiratory volume in 3 s (FEV3)/FVC ratio for Latin, black, and white adults; to ascertain comparative variability of the FEV1/FVC ratio, the FEV3/FVC ratio, and forced expiratory flow, midexpiratory phase (FEF(25-75)) in never-smoking adults; to evaluate their utility in measuring the eff...

Tetrahydrobiopterin (BH4) is an essential cofactor for the production of nitric oxide (NO) and supplementation with BH4 improves NO-dependent vasodilation. NO also reduces sympathetic vasoconstrictor responsiveness in resting and contracting skeletal muscle. Thus, we hypothesized that supplementation with BH4 would blunt sympathetic vasoconstrictor responsiveness in resting and contracting skel...

Lung function studies in middle-aged subjects predict cardiovascular disease mortality. We studied whether greater loss of forced vital capacity (FVC) early in life predicted incident hypertension. The sample was 3205 black and white men and women in the Coronary Artery Risk Development in Young Adults Study examined between 1985 and 1986 (Coronary Artery Risk Development in Young Adults year 0...

BACKGROUND In the context that accurate measurement of FVC is important in diagnosing airflow obstruction and in assessing restriction, strategies to achieve reliable and accurate FVC measurement have drawn much attention. OBJECTIVES Because the rate of achieving end-of-test criteria during spirometry has been shown to be low, with resultant under-recording of the FVC, the current study propo...

BACKGROUND We aimed to investigate the effects of spinal immobilization devices on pulmonary functions. METHODS This study was a cross-over trial in healthy volunteer subjects; 60 volunteers were included. We performed a full spirometry in the supine position, and forced vital capacity (FVC), forced expiratory volume in one second (FEV1) and FEV1/FVC were recorded in all subjects. Then, Phila...

The partial effective times of the expiratory spirogram were calculated in 80 normal non-smoking subjects aged from 20 to 69 years and in 30 patients aged from 30 to 58 years with chronic bronchitis. Of these patients, 28 had a normal FEV1/FVC ratio, while the other two had a low ratio. Partial effective times were calculated for 10% segments of the expired FVC from total lung capacity (0% FVC)...