A proportion of U.S. veterans returning from Iraq and Afghanistan have experienced mild traumatic brain injury (mTBI), which is associated with increased risk for developing posttraumatic stress disorder (PTSD). Prolonged Exposure (PE) has proven effectiveness in the treatment of PTSD; however, some clinicians have reservations about using PE with individuals with a history of mTBI. We examined...

OBJECTIVES Analyze the contribution of mild traumatic brain injury (mTBI) and/or posttraumatic stress disorder (PTSD) to the endorsement of postconcussive (PC) symptoms during Post Deployment Health Assessment. Determine whether a combination of mTBI and PTSD was more strongly associated with symptoms than either condition alone. METHODS Cross-sectional study design where both the exposure, m...

Background Hydrogen sulfide (H2S) is a crucial signaling molecule with a wide range of physiological functions. Previously, we confirmed that stress-induced depression is accompanied with disturbance of H2S generation in hippocampus. The present work attempted to investigate the inhibitory effect of H2S on chronic unpredictable mild stress-induced depressive-like behaviors and the underlying me...

background and purpose: medical education is a laborious program which may give negative consequences on the physical and psychological health of medical students. the aims of this study were to evaluate psychological distress among malay medical students and to assess its relationship with their lifestyle. methods: a cross-sectional study was conducted among 221 malay medical students. psychol...

To study effects of salicylic acid (SA) treatments (0, 0.5, 1 and 2 mM) in two forms of seed priming (for 24 h) and spraying on seedling at 4-6 leaf stage an experiment was conducted on periwinkle (Catharanthus roseus Don.) with and without exposure to a mild cold stress of 8 °C (for 32 h). Seeds were sown in trays containing peat-based substrate (with 20% sandy loam field soil). Transplants of...

The objective of this study was to investigate the role of β-aminobutyric acid(BABA) (0, 300µM) in reduction of oxidative damages in leaves and roots of Brassica napus L. under drought stress (0, -0.2, -0.4 MPa). β-aminobutyric acid was investigated as an internal regulator hormone and its role in defense  mechanisms against biotic and abioticstresses. In this study, BABA pretreatment prevented...

Two mild stress paradigms were used in the present study: acute (i.e. three injections of saline over 24 h) and subchronic (i.e. single daily injection of saline for 7 d). These mild stress procedures did not alter the behaviour of wild-type mice in the forced swim test. However, male BDNF+/- mice exhibited increased immobility in the forced swim test after mild stress. This genotypic differenc...

The extent to which early stress exposure is detrimental to darwinian fitness may depend on its severity, with mild stress exposure actually having a stimulatory and, possibly, beneficial effect through a hormetic response to the stressful stimulus. We need to understand such hormetic processes to determine how the early environment can help shape a phenotype adapted to the conditions the organ...