background: interest in tatera indica rodent arises mostly because it is believed that this species is survived among four subspecies reported from iran, two of which exist in khuzestan province. in addition, it might has a role as res­ervoir hosts of zoonotic cutaneous leishmaniasis in the transmission of leishmania major in some of the widespread asian foci including southwestern iran. method...

Mitochondrial markers are still often used alone to identify evolutionary units, despite widespread evidence for processes such as incomplete lineage sorting or introgressive hybridization that may blur past population history. The combination of mitochondrial DNA data with other sources of information (morphology, nuclear genes) is a powerful tool to reveal when and why mitochondrial markers a...

BACKGROUND Previous studies have shown that early life nutrition can modulate the development of white adipose tissue and thereby affect the risk on obesity and metabolic disease later in life. For instance, postnatal feeding with a concept infant milk formula with large, phospholipid coated lipid droplets (Concept, Nuturis®), resulted in reduced adiposity in adult mice. The present study inves...

Mutations in parkin lead to early-onset autosomal recessive Parkinson's disease (PD) and inactivation of parkin is thought to contribute to sporadic PD. Adult knockout of parkin in the ventral midbrain of mice leads to an age-dependent loss of dopamine neurons that is dependent on the accumulation of parkin interacting substrate (PARIS), zinc finger protein 746 (ZNF746), and its transcriptional...

The bioinvasion of the Mediterranean from the Red Sea via the Suez Canal, called Lessepsian bioinvasion, was used as a way to uncover the invading potential of different genetic clades. Populations of blotchfin dragonet Callionymus filamentosus were assessed, based on 2 mitochondrial markers (control region and cytochrome oxidase 1) and 2 nuclear markers (2nd intron of the ribosomal protein S7 ...

Saturated free fatty acids (FFAs) have been implicated in the increase of oxidative stress, mitochondrial dysfunction, endoplasmic reticulum (ER) stress, autophagy, and insulin resistance (IR) observed in skeletal muscle. Previously, we have shown that palmitate-induced mitochondrial DNA (mtDNA) damage triggers mitochondrial dysfunction, mitochondrial reactive oxygen species (mtROS) production,...

BACKGROUND Cigarette smoking is the major risk factor for COPD, leading to chronic airway inflammation. We hypothesized that cigarette smoke induces structural and functional changes of airway epithelial mitochondria, with important implications for lung inflammation and COPD pathogenesis. METHODS We studied changes in mitochondrial morphology and in expression of markers for mitochondrial ca...

An extensive search for recombination between mitochondrial markers was carried out in Paramecium tetraurelia. Thirty-two combinations, altogether involving 24 different markers, were studied. The markers belonged to the three main categories of mitochondrial mutations presently available in this organism, (a) Spontaneous or UV-induced antibiotic resistance mutations, most probably affecting mi...