Osteogenesis imperfecta (OI), a congenital bone disorder, is caused by mutations in COL1A1 and COL1A2 genes, leading to deficiency of type I collagen. The high resolution melting (HRM) analysis has been used for detecting mutations, polymorphisms and epigenetic alteration in double-stranded DNAs. This study was to evaluate the potential application of HRM analysis for identifying gene mutations...

OBJECTIVE Osteogenesis imperfecta (OI) is a rare connective tissue and bone disease that results in a bone fragility of varying severity. The objective was to determine and describe the OI in the Valencia Region (VR) during the period 2004 to 2014. METHODS From the Rare Diseases Information System of the VR (SIER-CV) patients from 2004 to 2014 with the codes of the International Classificatio...

Osseointegration can be defined as a direct structural and functional link between bone implant surface. Asymptomatic rigid fixation of the alloplastic material in is crucial for stability long-term success dental treatment. The connection surrounding tissue extremely dynamic. This interaction basis formation new structure—the implant-tissue interface. process osseointegration combination biolo...

INTRODUCTION Osteogenesis imperfecta is a heritable disorder affecting bone and tooth development. Malocclusion is frequent in those affected by osteogenesis imperfecta, but this has not been studied in detail. The purpose of this study was to describe and quantify the severity of malocclusions in patients with osteogenesis imperfecta. METHODS Articulated dental casts were obtained from 49 pa...

Osteogenesis is a complex series of events involving the differentiation of mesenchymal stem cells to generate new bone. In this study, we examined the effect of pulsed electromagnetic fields (PEMFs) on cell proliferation, alkaline phosphatase (ALP) activity, mineralization of the extracellular matrix, and gene expression in bone marrow mesenchymal stem cells (BMMSCs) during osteogenic differen...

Background: Osteogenesis imperfecta (OI) is a genetically determined disorder of connective tissue. In this article we reviewed epidemiology, types OI, pathophysiology, symptoms and potential therapies.Material methods: This paper was based on medical articles collected in PubMed from 2006 to 2022, websites books. The research has been done by looking through key words such as: „osteogenesis im...

Osteogenesis Pulsatile pressure assists early osteogenesis evaluation onto a 3D-printed soft hydrogel. Article 2202163 by Ki-Taek Lim and co-workers demonstrates the use of short-term stimulation its effect on proliferation, radical scavenging, stem cells. The results highlight transcriptomic changes in cells toward bone regeneration.

introduction: the objective of this study was to evaluated effect of retinoic acid (ra) on the tibia osteogenesis in the chick embryos. materials and methods: for this purpose 0.75mg ra dissolved in 2ml dimthylsulfoxide (dmso) was droped on the limb bud of chick embryos at sixth day of incubation. the osteogenesis of tibia in ra-treated embryos were compared with normal control and dmso-treated...

OBJECTIVE Umbilical mesenchymal stem cells (UMSCs) is one of most popular regenerative medical source of bone replacement therapy in both clinical and scientific researches. However, it is still low effective to induce the osteogenesis of hUMSCs. In this study, we aimed to elucidate the roles of DNA methyltransferase 3B (DNMT3B) in the osteogenesis of hUMSCs. MATERIALS AND METHODS Knockdown D...