pseudomonas aeruginosa is an opportunistic pathogen that causes a variety of infections in compromised patients. the ability of pseudomonas aeruginosa to produce chronic infection is based in part on its ability to biosynthesis of biofilm, and alginate is the major polysaccharide in the synthesized biofilm. so alginate degradation is very essential in the dispersion of pseudomonas aeruginosa bi...

biofilm of pseudomonas aeruginosa, an opportunistic pathogen, can cause serious health problems, such as chronic infections, especially in immunocompromised patients. many studies have suggested administration of new generation of antibiotics, as p. aeruginosa biofilms have developed high resistance to antimicrobial drugs. this study reports the inhibitory effect of three medicinal plant extrac...

objective(s): pseudomonas aeruginosa is a nosocomial pathogen resistant to most antimicrobial treatments. furthermore, it persists in adverse environments thereby forming biofilms on various surfaces. researchers have therefore focused on antibiofilm strategies using nanoparticles due to their unique physicochemical properties. superparamagnetic iron oxide nanoparticles (sionps) have recently s...

The success of Pseudomonas species as opportunistic pathogens derives in great part from their ability to form stable biofilms that offer protection against chemical and mechanical attack. The extracellular matrix of biofilms contains numerous biomolecules, and it has recently been discovered that in Pseudomonas one of the components includes β-sheet rich amyloid fibrils (functional amyloid) pr...

We here describe two novel lytic phages, KT28 and KTN6, infecting Pseudomonas aeruginosa, isolated from a sewage sample from an irrigated field near Wroclaw, in Poland. Both viruses show characteristic features of Pbunalikevirus genus within the Myoviridae family with respect to shape and size of head/tail, as well as LPS host receptor recognition. Genome analysis confirmed the similarity to ot...

Pseudomonas aeruginosa is a highly versatile opportunistic pathogen and its ability to produce biofilms is a direct impediment to the healing of wounds and recovery from infection. Interest in anti-microbial peptides (AMPs) has grown due to their potential therapeutic applications and their possible use against antibiotic resistant bacteria. LL-37 is the only cathelicidin expressed by humans. I...

Introduction A biofilm is an organizational community of bacteria adherent to a surface and encompassed in a self-fashioned exopolysaccharide matrix. Biofilm are complex communities of microorganisms that develop on surfaces in diverse environments. Bacteria in biofilms have an exclusive multicellular architecture and augmented resistance to host fortifications and antimicrobials. Biofilm was n...

This chapter aims to describe the early stages of biofilm formation, particularly on abiotic surfaces, by focusing on Pseudomonas aeruginosa. Specifically, we will dissect the early steps in the establishment of a multicellular community: (i) translocation to the surface from a free-swimming planktonic lifestyle, (ii) initial or reversible attachment, and finally (iii) irreversible attachment. ...

Bacteria often thrive in natural environments through a sessile mode of growth, known as the biofilm. Biofilms are well-structured communities and their formation is tightly regulated. However, the mechanisms by which interspecies interactions alter the formation of biofilms have not yet been elucidated in detail. We herein demonstrated that a quorum-sensing signal in Pseudomonas aeruginosa (th...