introduction: although bacteria producing biofilm are more resistance to antimicrobial agents, biofilm formation can stimulated by sub-minimal inhibitory concentrations (sub-mics) of some antimicrobial agents. therefore, we designed present study to investigate the  in vitro efficacy of several antibiotics (including ceftazidime, piperacillin, ticarcillin, carbenicillin, aztreonam, meropenem, g...

Background Pseudomonas is one of the predominant microorganisms of chronic lung infections. Bacteria growing in biofilm often develop multicellular, three-dimensional structures known as micro colonies. Pseudomonas colonizes the lungs by forming biofilm micro colonies throughout the lung. In this study, using Pseudomonas spp. artificial biofilm was grown on flow cell chamber and images were tak...

Background and Objective: Despite the critical importance of catheter as an indwelling medical device, its prolonged utilization in hospitalized patients may lead to infection. This study aimed to identify distribution of uropathogenic bacteria isolated from catheterized uro-oncology patients, their biofilm production, and antimicrobial resistance patterns to generally -used antibiotics. Mater...

BACKGROUND The contaminated contact lens provides Pseudomonas aeruginosa an ideal site for attachment and biofilm production. Continuous contact of the eye to the biofilm-infested lens can lead to serious ocular diseases, such as keratitis (corneal ulcers). The biofilms also prevent effective penetration of the antibiotics, which increase the chances of antibiotic resistance. METHODS For this...

The goal of this proposal is to identify biofilm-specific regulatory proteins involved in the regulation of initial biofilm formation that once inactivated, impair or arrest the biofilm formation process. We have identified 8 regulatory proteins which become sequentially phosphorylated/dephopshorylated during biofilm formation. Inactivation of sagS and bfiS arrested biofilm formation prior to t...

conclusions biofilm formation (both strong and weak) strongly correlated with psla gene carriage. biofilm formation also correlated with mbl and ampc β-lactamase production. more importantly, multiple-β-lactamase phenotype was associated with formation of strong biofilms. results biofilm formation was observed in 43.5% of the isolates, of which 66.7% produced strong and 33.3% formed weak biofil...

objective(s): bacterial biofilm formation causes many persistent and chronic infections. the matrix protects biofilm bacteria from exposure to innate immune defenses and antibiotic treatments. the purpose of this study was to evaluate the biofilm formation of clinical isolates of pseudomonas aeruginosa and the activity of zinc oxide nanoparticles (zno nps) on biofilm. materials and methods: aft...

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background and objectives: pseudomonas aeruginosais an important opportunistic pathogen. the mucoid strains of p. aeruginosa produce hyper viscous substances consisting mainly of alginate which have important roles in formation of biofilm.we investigated the effect of essential oil of matricaria chamomilla l. on biofilm production in p. aeruginosa. material and methods: p. aeruginosa 8821m was ...