Background & Objective: Securigera securidaca is a medicinal plant used in Persian folk medicine to decrease blood sugar. Nevertheless, there is some controversy about its effects. The current study investigated the hypoglycemic activity of the aqueous seed extract of S. securidaca. Materials & Methods: Sixty mature male Charles-River rats were categorized and divided randomly into 10 groups w...

Background and objectives: The seeds of Securigera securidaca (L.) Deg. & Dorf. (Fabaceae) are used as anti-diabetic remedy in Iranian folk medicine. The aim of the present study was to establish the callus and suspension culture of S. securidaca seeds for the first time and to determine the major secondary metabolites including cardiac glycosides and total ph...

      The search for indigenous natural antidiabetic agents is still ongoing. Securigera securidaca seeds are reputed in folk medicine for their value as an antidiabetic remedy, so the present study was carried out to investigate the hypoglycemic efficacy in both normal and streptozotocine (STZ)-induced diabetic rats. Hydroalcoholic extract of the seeds were administe...

Rosa damascena, Tripleurospermum disciforme and Securigera securidaca were used as disinfectant agents and for treatment of some disease in folk medicine of Iran. The antimicrobial effects of different fractions of seeds extract of S. securidaca, petals extract of R. damascena and aerial parts extract of T. disciforme were examined against some gram positive, gram negative and fungi by cup plat...