نتایج جستجو برای: small cell lung cancer
تعداد نتایج: 3069991 فیلتر نتایج به سال:
سرطان ریه یکی از قابل پیشگیریترین سرطانها است و مهمترین عامل ایجاد کننده آن سیگار است. سرطان ریه به دو شکل سرطان سلول کوچک ( small cell lung cancer ) و سرطان غیرسلول کوچک ( non small cell lung cancer ) شناخته میشود. سرطانهای غیرسلول کوچک شامل پاتولوژیهای گوناگونی است ولی علیرغم این گوناگونی، درمان مشابهی دارند. مرحلهبندی( staging ) دقیق سرطان ریه در ابتدای تشخیص بیماری اهمیت بسزایی دارد ...
Background and Objective: Lung cancer is the leading cancer killer and is the second most frequently diagnosed cancer behind prostate in men and breast cancer in women. Staging has a very important role in determination of disease extension and therefore in deciding about the kind of treatment. The aim of this study is showing the effect of surgical method in lung cancer staging and its impact ...
Background: It is well known that, at the time of the initial presentation of patients with non-small cell lung cancer, N-status is very important in accurate staging and avoiding inappropriate surgical procedures. Also, if mediastinal lymph node metastasis (N2) of non-small cell lung cancer (stage IIIA) is present, neoadjuvant (preoperative) chemora-diotherapy is indicated therefore a quick an...
Background and purpose: Several studies have been carried out on re-cut and de-stained sections regarding prostate biopsies and cytologic specimens of squamous cell carcinoma. However, few studies on lung biopsy are done. Due to small size of lung biopsies and for the prevention of lung rebiopsy, in this study P63 staining intensity between re-cut and de-stained slides of patients, specimens ...
Aims: The backbone of treatment in advanced non-small cell lung cancer is platinum-based doublet chemotherapy. We intended to compare the effectiveness of two commonly used regimens in real world practice. Methods: This single institute, parallel comparative post marketing study included 100 patients with chemo-naïve advanced (stage IIIB, IV) non-small cell lung cancer and Eastern Cooperative O...
Background and Aim: Lung cancer is the most common cause of cancer-related deaths wordwide and non-small cell lung cancer (NSCLC), especially adenocarcinoma, is the most common type of lung cancer. Most cases of adenocarcinoma will occur due to KRAS mutations or EGFR mutations and amplifications. The polymorphism rs884225 which is associated with increased EGFR expression is located in the 3'UT...
Aims: The backbone of treatment in advanced non-small cell lung cancer is platinum-based doublet chemotherapy. We intended to compare the effectiveness of two commonly used regimens in real world practice. Methods: This single institute, parallel comparative post marketing study included 100 patients with chemo-naïve advanced (stage IIIB, IV) non-small cell lung cancer and Eastern Cooperative O...
background: the aberrant expression of dickkopf-1 (dkk1), triose phosphate isomerase (tpi) and fatty acid binding-protein 5 (fabp5) in lung cancer tissues and their presence in secretome of lung cancer cell lines were reported. here, serum levels of these molecules in lung cancer patients were compared to those in a healthy control group. materials and methods: the patients’ group consisted of ...
مقدمه: پلی مورفیسم ژنتیکی در ژن های درگیر در ترمیم dna ممکن است با کاهش ظرفیت ترمیمی محصولات این ژن ها، سبب افزایش خطر ابتلا به سرطان های مختلف در انسان شود. ژن xrcc1 یکی از ژن های مهم در ترمیم dna می باشد. در این مطالعه، پلی مورفیسم gln399arg در ژن xrcc1 و ارتباط آن با استعداد ابتلا به سرطان ریه در جمعیت استان فارس مورد بررسی قرار گرفت. روش ها: در این مطالعه ی مورد- شاهدی، dna استخراج شده از 1...
Tumour cells may be resistant to radiotherapy that results in unsuccessful cancer treatment in patients. The aim of this study was to evaluate the sensitizing effect of atorvastatin (ATV) on breast cancer (MDA-MB-231) and non-small cell lung cancer (A-549) cells following exposure to ionizing radiation (IR). These cells were treated with ATV and exposed to X-ray at dose 4 Gy. The radiosensitizi...
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