resistance to thyroid hormone is an uncommon condition. we report the clinical and laboratory findings of a case with both resistance to thyroid hormone and, a reduced capacity to produce and respond to thyroid hormone. rth is a disorder characterized by elevated circulating thyroid hormones, state of non-suppressed pituitary tsh secretion and refractoriness to hormone action in peripheral tiss...

background beta-thalassemia is the most common hematology disease in human and leptin is one of the hormone that produce by adiposities cells. the purpose of this study was to investigate the relationship between serum leptin level and thyroid hormones in children with major beta-thalassemia. materials and methods this descriptive-cross sectional study was performed on 90 children aged 6-16 yea...

Ectopic thyroid tissue results from abnormal embryologic development and migration of the thyroid gland. True malignant transformation in ectopic thyroid tissue is extremely rare and is always diagnosed after surgical excision of the lesion by pathology examinations. There are well-documented cases of ectopic thyroid cancer while primary tumoral lesion occurs in the orthotopic thyroid, but only...

background thyroid hormones play an important role in lipid metabolism. overt hypothyroidism is known to be associated with increased lipid profiles, but the effect of subclinical hypothyroidism (sch) on lipid profile remains controversial. objectives the aim of this study was to assess the association between thyroid disorders and serum lipid levels. materials and methods the present study was...

Background: Vitiligo is a pigmentary disorder of the skin, which has been reported in association with thyroid disorders. Objective: The aim of this study was to assess thyroid disorders in vitiligo patients. Patients and Methods: In this case-control study, thyroid function tests were evaluated in seventy patients with vitiligo and compared with a control group. Results: Nine of seventy patien...

BACKGROUND Dendritic cells play key roles in thymic histophysiology and histopathology. Therefore, we analyzed the immunotopographical distribution of cells expressing markers of dendritic cells and macrophages in postnatal human thymus. MATERIALS AND METHODS The streptavidin-biotin peroxidise-labeled (LSAB) and the double-LSAB/alkaline phosphatase/anti-alkaline phosphatase (APAAP) immunohist...