extensive research in the last decade has defined that most chronic diseases display dysregulation of multiple cell signaling pathways that have been linked to inflammation. neuroinflammation is reaction of living nervous tissue to injury. it may be initiated in response to neurological disease. including infection, traumatic brain injury, toxic metabolites and autoimmunity. the natural compoun...

The rapid developments in neuroscientific techniques raise high expectations among the general public and therefore warrant close monitoring of the translation to the media and daily-life applications. The need of empirical research into neuroscience communication is emphasized by its susceptibility to evoke misconceptions and polarized beliefs. As the mass media are the main sources of informa...

Neuroscience has recently contributed a lot to the understanding of aesthetic experience features. Science, art and creativity are not really distinctively different entities. The parallelism seen between the properties of art and organizational principals of the brain has been highlighted through neuroaesthetic studies. Aesthetic as a subjective experience has comprehensively been studies thro...

The absence of mouse pharmacokinetic reference data hinders translation. An analysis of recent literature highlights a systematic lack of discussion regarding rationale for the selection of dosing paradigms in preclinical studies, and in particular for neuroscience studies in which the lack of brain penetration can limit target-organ exposure. We propose solutions to improve study design.

The dream of cognitive neuroscience has always been a seamless integration of cognitive representations with neural machinery, but—despite decades of work—fundamental gaps remain. Part of the problem is that many contemporary theories of cognition are formulated in terms of representations and computations that are quite different from those used in computational neuroscience. Bridging this gap...

This article attends to the processes through which neuroscience and the neuro are enacted in a specific context: a translational neuroscience research group that was the setting of an ethnographic study. The article therefore provides a close-up perspective on the intersection of neuroscience and translational research. In the scientific setting we studied, the neuro was multiple and irreducib...

the first necessary step in researches to treat spinal cord injuries (sci) is to understand complexities related to the neurophysiology and neurobiology changes of human sci with stem cell therapy(sct). the aim of this study is to identify these changes. the level of injuries is important in treatment and determination of this injury (whether it is complete, incomplete, or discomplete) is valua...

Students with transcription disabilities (dysgraphia/impaired handwriting, n = 13 or dyslexia/impaired word spelling, n = 16) or without transcription disabilities (controls) completed transcription and translation (idea generating, planning, and creating) writing tasks during fMRI connectivity scanning and compositions after scanning, which were coded for transcription and translation variable...