background: one-third of the world’s population is currently infected by tubercle bacillus. this study was performed to evaluate epidemiological and clinical aspects of confirmed cases of tuberculosis infections in a seven-year time period, between years of 2002 to 2008, in the city of hamadan, west of iran. materials and methods: in this descriptive retrospective study, medical records of 375 ...

conclusions the results of the current study showed a high rate of co-infection of m. tuberculosis and p. jirovecii in the iranian patients with hiv. as the immune system condition worsened, the probability of occurrence of pneumocystis pneumonia (pcp) increased. therefore, more specific, most rapid and sensitive tests should be utilized for diagnosis of pcp in this group of patients. results a...

a study on clinical signs of tuberculosis patients in urmia a gholami , bsc l moosavi jahromi ,bsc received: 11 aug, 2009 accepted: 25 oct, 2009 abstract background & aims: tuberculosis is a major health problem worldwide, especially in developing countries. the warning signs of pulmonary tuberculosis are chronic cough with sputum that is usually accompanied by bloody sputum, and sometimes the ...

background: tuberculosis is one of the infectious diseases worldwide that has resurgence by the aids epidemic and led to the rise of drug-resistant tuberculosis patients. thus, it seems essential to monitor the drug susceptibility in tuberculosis patients. the new high resolution melting (hrm) method is simple, rapid and inexpensive for detection of the mutations responsible for drug resistance...

tuberculosis is a major health problem in iran and its laryngeal involvement is not uncommon. laryngeal tuberculosis is so infectious and delay in diagnosis and treatment could result spread of disease and causes divesting complications. we reviewed clinical and para-clinical characteristics of patients with laryngeal tuberculosis in iran. in a cross sectional study, patients with laryngeal tub...

We investigated the use of DNA amplification by polymerase chain reaction (peR) for detection of Mycobacterium tuberculosis in 300 patients who were suspected of having pulmonary tuberculosis and compared the results with culture results which were performed in parallel with PCR. Two-thirds of each sample was processed for smear and culture by standard methods and one-third was prepared fo...

Background: Matrix metalloproteases (MMPs) are multi-chain proteins that regulated by tissue inhibitor of metalloproteinases (TIMP) and several other mechanisms. This Includes transcription regulation and protein form secretion. The roles of MMPs in wound healing and tissue repair. In tuberculosis (TB), the activity of MMPs is increased and TIMP inhibitors decrease activity. Therefore, in tuber...

Background: Lectin pathway mediates complement activation, which is activated by many microorganisms. This study aimed at determining the serum levels of mannose-binding lectin (MBL) in patients with pulmonary tuberculosis, assessing its relationship to antiuberculosis treatment response, and comparing them with a control group.    Methods: This cross-sectional study was conducted on...