metastasis of gastroesphageal junction (gej) adenocarcinoma in skeletal muscle is rare and primary sites for skeletal muscle metastases are usually lung, renal and colorectal cancer. we have encountered with the first case report of solitary psoas muscle metastasis of gej adenocarcinoma. here we describe a 65 years old man was diagnosed with gej adenocarcinoma in tertiary hospital, tehran, iran...

the rectum villous tumour is an uncommon pathology in paediatrics, it represent 1% of all the children's malign tumours. an eleven-year-old girl present a rectal adenocarcinoma developed from a villous tumour. the aim of this study is to assess , an overview of litterature, the frequency of rectum villous tumours; to specify the value of the clinical examination , of the radiologic finding in t...

156 iranian patients with primary malignant tumors of the small intestine were reviewed. malignant lymphoma was the most common tumor type, comprising 128 patients (82%), followed by adenocarcinoma (22 patients, 14.1 %), leiomyosarcoma (4 patients, 2.56%) and carcinoid tumor (2 patients, 1.28%). lymphomas and adenocarcinomas were primarily located in the duodenum or jejunum, whereas leiomyosarc...

cancer starts with a change in one single cell. this change may be initiated by external agents and genetic factors. cancer is a leading cause of death worldwide and accounts for 7.6 million deaths (around 13% of all deaths) in 2008. lung, stomach, liver, colon and breast cancer cause the most cancer deaths each year. in this review, different aspects of gastric cancer; including clinical, path...

BACKGROUND Several indices have been developed to predict survival of brain metastases (BM) based on prognostic factors. However, such models were designed for general brain metastases from different kinds of cancers, and prognostic factors vary between cancers and histological subtypes. Recently, studies have indicated that epidermal growth factor receptor (EGFR) mutation status may be a poten...

background: prostatic adenocarcinoma is the most prevalent cancer and the second cause of cancer-related death among men. human papilloma virus (hpv) considered as a preventable risk factor for prostatic adenocarcinoma. in this study, we detected the frequency of hpv infection in prostatic adenocarcinoma and benign prostatic hyperplasia (bph) in isfahan. materials and methods: in this study, 12...

objective(s): prostate cancer is the world’s leading cause of cancer and the second cause of cancer-related death in men after lung cancer. differentiation of prostate adenocarcinoma from benign prostate lesions and hyperplasia sometimes cannot be done on the basis of morphologic findings. considering the fact that in the prostate adenocarcinoma there is no basal cell layer, basal cell markers ...

Long-term studies of the carcinogenicity of N-methyl-N-nitrosourea (MNU) in inbred guinea pigs were undertaken to develop an animal model of pancreatic adenocarcinoma. MNU, freshly, dissolved in 0.015 M sodium citrate buffer, pH 6.0, was administered by gavage once weekly at a dose of 10 mg/kg body weight to inbred strain 13 guinea pigs. By 27 weeks, 54% of guinea pigs given MNU weekly died, mo...

Two commonly occurring genetic aberrations of human prostate cancer [i.e., overexpression of a mitogenic polypeptide (fibroblast growth factor 8, isoform b or FGF8b) and loss of function of PTEN tumor suppressor] were recapitulated into a new combinatorial mouse model. This model harboring the Fgf8b transgene and haploinsufficiency in Pten, both in a prostate epithelium-specific manner, yielded...