in this study, the possible involvement of l-type voltage-operated calcium channels in the vasorelaxant effect of the flavonoid quercetin was investigated, using the isolated aortic rings from normal male rats. addition of quercetin (0.1 µm-1 mm) caused a significant dose-dependent relaxation of noradrenaline (na)- and kcl-preconstricted rings and nifedipine attenuated this response, especially...

aortic dissection begins with the formation of a tear in the aortic intima, and it directly exposes an underlying diseased medial layer to the driving force of the intraluminal blood. this blood penetrates the diseased medial layer and cleaves the media longitudinally, thereby dissecting the aortic wall. herein, we report the case of a 38-year-old woman, who presented with chest pain and dyspne...

common variable immunodeficiency (cvid) is the most common symptomatic primary immunodeficiency disease, predisposing the patients to various tissue involvement and organ damage. here a 16-year-old boy is presented who was referred to our center with cough, dyspnea,cyanosis, and history of recurrent pneumonia. the diagnosis of cvid was made according to reduction all serum immunoglobulin levels...

La aortitis se refiere a la inflamación de aorta, que puede ser causa no infecciosa o infecciosa, diagnosticándose generalmente forma incidental tras estudios histopatológicos piezas quirúrgicas aorta. Se presentan dos casos pacientes acudieron por falla cardíaca y aneurisma aorta severa, con necesidad cirugía. El reporte patología informó: aortitis. Luego complementarios, concluyó trataba una ...

Awareness of the variation and renal vascular abnormality at retroperitoneal space surgeries such as kidney surgery and transplantation is very important and necessary. Complexity in the veins development of the kidney area of fetus leads to a series of changes in the production of these veins, including the extra kidney vein, and the posterior aorta vein. In this case report, we present a case...

traumatic false aneurysm of the thoracic aorta is not uncommon. but accordingly this case is unusual in its ten year delay between injury and presentation and treatment. a victim of the iran-iraq war is presented with a false aneurysm of the thoracic aorta ten years after a bullet injury to the chest and thoracic spine. penetrating chest wounds, mechanisms of injury and diagnosis are also discu...

introduction: our previous studies showed that hydroalcoholic extract of leaf of vitis vinifera relaxes the phenylephrine-induced contraction in rat thoracic aorta. this effect was dependent on endothelial integrity and no-cgmp system. the vasorelaxant effect of extract was much lesser on kcl-induced contraction. we, therefore, postulated that k+ channels are involved. the main aim of the prese...

aortopulmonary window (apw) is a rare congenital malformation. it results from an incomplete division between the ascending aorta and the pulmonary artery. we describe a 26-year-old male, who presented with a grade ii exertional dyspnea and palpitations. echocardiography revealed an apw with an ascending aorta aneurysm. he underwent surgery under cardiopulmonary bypass without aortic cross-clam...

abdominal aortic coarctation is an extremely rare vascular pathology. its etiology can be congenital or acquired. here we present a case of acquired infrarenal abdominal coarctation in a 66-year-old woman who complained of low back and legs pain. she had no signs of resting lower limb ischemia, with diminished distal pulses and normal blood pressure in upper and lower extremities. magnetic reso...